Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066422627> ?p ?o ?g. }
- W2066422627 endingPage "766.e1" @default.
- W2066422627 startingPage "762" @default.
- W2066422627 abstract "To compare the effects of trimethoprim-sulfamethoxazole vs placebo in reducing the risk of recurrences of Toxoplasma gondii retinochoroiditis.Single-center, prospective randomized double-masked clinical trial.A total of 95 patients from Campinas, Brazil, with active recurrent Toxoplasma gondii retinochoroiditis were included. The initially active toxoplasmosis lesions were successfully treated in all cases using trimethoprim-sulfamethoxazole (800 mg/160 mg) twice daily for 45 days. Subsequently, 5 patients dropped out of the study. The remaining patients were randomized to Group 1 (trimethoprim/sulfamethoxazole tablet every 2 days) or Group 2 (identical placebo tablet every 2 days). Randomization was 1:1, was stratified by sex, and used block sizes of 4. The primary outcome was recurrent toxoplasmosis retinochoroiditis within 1 year, and the secondary outcome was a 1-year change in best-corrected visual acuity (BCVA) (ETDRS chart).The incidence of recurrent toxoplasmosis retinochoroiditis within 12 months was 0 of 46 (0%) and 6 of 47 (12.80%) in the trimethoprim-sulfamethoxazole and placebo groups, respectively (P = .026). Visual acuity improvements in the 2 groups were similar. No treatment-limiting toxicity was observed.Trimethoprim/sulfamethoxazole therapy resulted in a 100% reduction in the recurrence of Toxoplasma gondii retinochoroiditis over 1 year of treatment." @default.
- W2066422627 created "2016-06-24" @default.
- W2066422627 creator A5000833028 @default.
- W2066422627 creator A5017892600 @default.
- W2066422627 creator A5028312359 @default.
- W2066422627 creator A5035384333 @default.
- W2066422627 creator A5049934228 @default.
- W2066422627 creator A5070293832 @default.
- W2066422627 date "2014-04-01" @default.
- W2066422627 modified "2023-10-01" @default.
- W2066422627 title "Trimethoprim-Sulfamethoxazole Versus Placebo to Reduce the Risk of Recurrences of Toxoplasma Gondii Retinochoroiditis: Randomized Controlled Clinical Trial" @default.
- W2066422627 cites W1965292366 @default.
- W2066422627 cites W1966735715 @default.
- W2066422627 cites W2025618899 @default.
- W2066422627 cites W2042765236 @default.
- W2066422627 cites W2043452170 @default.
- W2066422627 cites W2057525476 @default.
- W2066422627 cites W2098922030 @default.
- W2066422627 cites W2108632762 @default.
- W2066422627 cites W2110452497 @default.
- W2066422627 cites W2118833767 @default.
- W2066422627 cites W2119744132 @default.
- W2066422627 cites W2169703759 @default.
- W2066422627 doi "https://doi.org/10.1016/j.ajo.2013.12.022" @default.
- W2066422627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24388839" @default.
- W2066422627 hasPublicationYear "2014" @default.
- W2066422627 type Work @default.
- W2066422627 sameAs 2066422627 @default.
- W2066422627 citedByCount "62" @default.
- W2066422627 countsByYear W20664226272014 @default.
- W2066422627 countsByYear W20664226272015 @default.
- W2066422627 countsByYear W20664226272016 @default.
- W2066422627 countsByYear W20664226272017 @default.
- W2066422627 countsByYear W20664226272018 @default.
- W2066422627 countsByYear W20664226272019 @default.
- W2066422627 countsByYear W20664226272020 @default.
- W2066422627 countsByYear W20664226272021 @default.
- W2066422627 countsByYear W20664226272022 @default.
- W2066422627 countsByYear W20664226272023 @default.
- W2066422627 crossrefType "journal-article" @default.
- W2066422627 hasAuthorship W2066422627A5000833028 @default.
- W2066422627 hasAuthorship W2066422627A5017892600 @default.
- W2066422627 hasAuthorship W2066422627A5028312359 @default.
- W2066422627 hasAuthorship W2066422627A5035384333 @default.
- W2066422627 hasAuthorship W2066422627A5049934228 @default.
- W2066422627 hasAuthorship W2066422627A5070293832 @default.
- W2066422627 hasConcept C120665830 @default.
- W2066422627 hasConcept C121332964 @default.
- W2066422627 hasConcept C126322002 @default.
- W2066422627 hasConcept C141071460 @default.
- W2066422627 hasConcept C142724271 @default.
- W2066422627 hasConcept C159654299 @default.
- W2066422627 hasConcept C168563851 @default.
- W2066422627 hasConcept C203014093 @default.
- W2066422627 hasConcept C204243189 @default.
- W2066422627 hasConcept C204787440 @default.
- W2066422627 hasConcept C27081682 @default.
- W2066422627 hasConcept C2778062946 @default.
- W2066422627 hasConcept C2778128430 @default.
- W2066422627 hasConcept C2779425571 @default.
- W2066422627 hasConcept C2780728791 @default.
- W2066422627 hasConcept C501593827 @default.
- W2066422627 hasConcept C61511704 @default.
- W2066422627 hasConcept C71924100 @default.
- W2066422627 hasConcept C86803240 @default.
- W2066422627 hasConcept C89423630 @default.
- W2066422627 hasConceptScore W2066422627C120665830 @default.
- W2066422627 hasConceptScore W2066422627C121332964 @default.
- W2066422627 hasConceptScore W2066422627C126322002 @default.
- W2066422627 hasConceptScore W2066422627C141071460 @default.
- W2066422627 hasConceptScore W2066422627C142724271 @default.
- W2066422627 hasConceptScore W2066422627C159654299 @default.
- W2066422627 hasConceptScore W2066422627C168563851 @default.
- W2066422627 hasConceptScore W2066422627C203014093 @default.
- W2066422627 hasConceptScore W2066422627C204243189 @default.
- W2066422627 hasConceptScore W2066422627C204787440 @default.
- W2066422627 hasConceptScore W2066422627C27081682 @default.
- W2066422627 hasConceptScore W2066422627C2778062946 @default.
- W2066422627 hasConceptScore W2066422627C2778128430 @default.
- W2066422627 hasConceptScore W2066422627C2779425571 @default.
- W2066422627 hasConceptScore W2066422627C2780728791 @default.
- W2066422627 hasConceptScore W2066422627C501593827 @default.
- W2066422627 hasConceptScore W2066422627C61511704 @default.
- W2066422627 hasConceptScore W2066422627C71924100 @default.
- W2066422627 hasConceptScore W2066422627C86803240 @default.
- W2066422627 hasConceptScore W2066422627C89423630 @default.
- W2066422627 hasFunder F4320320997 @default.
- W2066422627 hasIssue "4" @default.
- W2066422627 hasLocation W20664226271 @default.
- W2066422627 hasLocation W20664226272 @default.
- W2066422627 hasOpenAccess W2066422627 @default.
- W2066422627 hasPrimaryLocation W20664226271 @default.
- W2066422627 hasRelatedWork W1995054522 @default.
- W2066422627 hasRelatedWork W2011439907 @default.
- W2066422627 hasRelatedWork W2108699896 @default.
- W2066422627 hasRelatedWork W2279903097 @default.
- W2066422627 hasRelatedWork W2425419542 @default.
- W2066422627 hasRelatedWork W3093753935 @default.