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• W2066426041 abstract "Increasing evidence suggests that bacterial and viral superantigens are involved in immune-mediated disease. Studies using an animal model for multiple sclerosis show that superantigens can induce relapses and bring into play autoreactive T cells with restricted usage of T cell receptor V beta families that may be indirectly involved in the initial episode of disease. This may also involve epitope spreading. Superantigens have also been implicated in other autoimmune diseases such as rheumatoid arthritis and psoriasis. Superantigens encoded by viruses such as mouse mammary tumor virus play an important role in disease progression." @default.
• W2066426041 created "2016-06-24" @default.
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• W2066426041 date "1998-08-01" @default.
• W2066426041 modified "2023-10-10" @default.
• W2066426041 title "Modulation of disease by superantigens" @default.
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• W2066426041 doi "https://doi.org/10.1016/s0952-7915(98)80122-2" @default.
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