Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066458114> ?p ?o ?g. }
- W2066458114 endingPage "9168" @default.
- W2066458114 startingPage "9161" @default.
- W2066458114 abstract "Abstract We have synthesized two lactose‐based molecular transporters, each containing seven guanidine residues attached to the lactose scaffold through ω‐aminocarboxylate linker chains of two different lengths, and have examined their cellular uptakes and intracellular and organellar localizations in HeLa cells, as well as their tissue distributions in mice. Both molecular transporters showed higher cellular uptake efficiencies than Arg8, and wide tissue distributions including the brain. Mitochondrial localization is of special interest because of its potential relevance to “mitochondrial diseases”. Interestingly, it has been found that the intracellular localization sites of the G7 molecular transporters—namely either mitochondria or lysosomes and endocytic vesicles—are largely determined by the linker chain lengths, or their associated lipophilicities." @default.
- W2066458114 created "2016-06-24" @default.
- W2066458114 creator A5002661162 @default.
- W2066458114 creator A5012341675 @default.
- W2066458114 creator A5020020153 @default.
- W2066458114 creator A5022553207 @default.
- W2066458114 creator A5030586134 @default.
- W2066458114 creator A5046016624 @default.
- W2066458114 creator A5050180670 @default.
- W2066458114 creator A5087294148 @default.
- W2066458114 date "2008-10-10" @default.
- W2066458114 modified "2023-10-18" @default.
- W2066458114 title "Novel Guanidine-Containing Molecular Transporters Based on Lactose Scaffolds: Lipophilicity Effect on the Intracellular Organellar Selectivity" @default.
- W2066458114 cites W1501833124 @default.
- W2066458114 cites W1523824033 @default.
- W2066458114 cites W1590085201 @default.
- W2066458114 cites W1963633899 @default.
- W2066458114 cites W1969217480 @default.
- W2066458114 cites W1974186613 @default.
- W2066458114 cites W1977943274 @default.
- W2066458114 cites W1988702147 @default.
- W2066458114 cites W1997103748 @default.
- W2066458114 cites W2004335248 @default.
- W2066458114 cites W2019144805 @default.
- W2066458114 cites W2024343679 @default.
- W2066458114 cites W2025067737 @default.
- W2066458114 cites W2029346749 @default.
- W2066458114 cites W2031804169 @default.
- W2066458114 cites W2032250529 @default.
- W2066458114 cites W2036828113 @default.
- W2066458114 cites W2040060119 @default.
- W2066458114 cites W2040885207 @default.
- W2066458114 cites W2042159082 @default.
- W2066458114 cites W2044494908 @default.
- W2066458114 cites W2053740745 @default.
- W2066458114 cites W2058622006 @default.
- W2066458114 cites W2061258627 @default.
- W2066458114 cites W2065116897 @default.
- W2066458114 cites W2066778206 @default.
- W2066458114 cites W2075231390 @default.
- W2066458114 cites W2089712488 @default.
- W2066458114 cites W2094787420 @default.
- W2066458114 cites W2103119315 @default.
- W2066458114 cites W2109782478 @default.
- W2066458114 cites W2113999599 @default.
- W2066458114 cites W2123650819 @default.
- W2066458114 cites W2124955411 @default.
- W2066458114 cites W2160863389 @default.
- W2066458114 cites W4238598813 @default.
- W2066458114 cites W4238611970 @default.
- W2066458114 cites W4250825896 @default.
- W2066458114 cites W4252004446 @default.
- W2066458114 doi "https://doi.org/10.1002/chem.200801160" @default.
- W2066458114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18770513" @default.
- W2066458114 hasPublicationYear "2008" @default.
- W2066458114 type Work @default.
- W2066458114 sameAs 2066458114 @default.
- W2066458114 citedByCount "24" @default.
- W2066458114 countsByYear W20664581142012 @default.
- W2066458114 countsByYear W20664581142013 @default.
- W2066458114 countsByYear W20664581142014 @default.
- W2066458114 countsByYear W20664581142016 @default.
- W2066458114 countsByYear W20664581142017 @default.
- W2066458114 countsByYear W20664581142018 @default.
- W2066458114 countsByYear W20664581142020 @default.
- W2066458114 countsByYear W20664581142021 @default.
- W2066458114 crossrefType "journal-article" @default.
- W2066458114 hasAuthorship W2066458114A5002661162 @default.
- W2066458114 hasAuthorship W2066458114A5012341675 @default.
- W2066458114 hasAuthorship W2066458114A5020020153 @default.
- W2066458114 hasAuthorship W2066458114A5022553207 @default.
- W2066458114 hasAuthorship W2066458114A5030586134 @default.
- W2066458114 hasAuthorship W2066458114A5046016624 @default.
- W2066458114 hasAuthorship W2066458114A5050180670 @default.
- W2066458114 hasAuthorship W2066458114A5087294148 @default.
- W2066458114 hasConcept C104317684 @default.
- W2066458114 hasConcept C111919701 @default.
- W2066458114 hasConcept C12554922 @default.
- W2066458114 hasConcept C149011108 @default.
- W2066458114 hasConcept C1491633281 @default.
- W2066458114 hasConcept C160408235 @default.
- W2066458114 hasConcept C185592680 @default.
- W2066458114 hasConcept C201399114 @default.
- W2066458114 hasConcept C2779463914 @default.
- W2066458114 hasConcept C2780557392 @default.
- W2066458114 hasConcept C28005876 @default.
- W2066458114 hasConcept C28859421 @default.
- W2066458114 hasConcept C41008148 @default.
- W2066458114 hasConcept C55493867 @default.
- W2066458114 hasConcept C79747257 @default.
- W2066458114 hasConcept C79879829 @default.
- W2066458114 hasConcept C86803240 @default.
- W2066458114 hasConcept C95444343 @default.
- W2066458114 hasConceptScore W2066458114C104317684 @default.
- W2066458114 hasConceptScore W2066458114C111919701 @default.
- W2066458114 hasConceptScore W2066458114C12554922 @default.
- W2066458114 hasConceptScore W2066458114C149011108 @default.
- W2066458114 hasConceptScore W2066458114C1491633281 @default.