FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066490140> ?p ?o ?g. }

• W2066490140 endingPage "1002" @default.
• W2066490140 startingPage "998" @default.
• W2066490140 abstract "Les mucormycoses sont des infections fongiques rares survenant surtout chez les immunodéprimés. Elles sont dues à des champignons filamenteux de type Mucorales. Les formes disséminées sont le plus souvent fatales. Le diagnostic, souvent difficile, doit être le plus précoce possible. La prise en charge consiste à instaurer rapidement un traitement antifongique avec la formulation lipidique d’amphotéricine B et à réaliser un large débridement chirurgical. En dépit d’un traitement optimal, la mortalité liée aux mucormycoses reste très importante. Nous rapportons un cas de mucormycose disséminée chez une patiente de 25 ans transplantée pulmonaire depuis neuf mois. Il existait une atteinte pulmonaire et thyroïdienne due à Absidia corymbifera. La patiente a survécu grâce à une chirurgie élargie, cervicale et thoracique, et à une bithérapie antifongique précoce associant la formulation lipidique d’amphotéricine B et posaconazole. L’émergence des mucormycoses chez les patients transplantés et leur mortalité importante incitent à trouver de nouvelles alternatives thérapeutiques. L’association du posaconazole avec la formulation lipidique d’amphotéricine B pourrait présenter un intérêt dans le traitement des mucormycoses disséminées. Mucormycosis is a rare fungal infection occurring most frequently in immunocompromised patients. The pathogens are filamentous fungi, order of Mucorales. Disseminated mucormycosis is a severe, life treating disease. Early diagnosis is a major determinant for prognosis, however, it remains difficult. The management consists in an early antifungal therapy using lipid formulation of amphotericin B associated with an extensive surgical debridement. Despite this therapeutic of choice, the mortality of disseminated mucormycosis remains high. We report the case of disseminated mucormycosis in a 25 years old woman 9 months after a pulmonary transplantation. The clinical presentation included pulmonary and thyroid localization and the pathogen was Absidia corymbifera. The patient survived thanks to a large surgical debridement, and an early antifungal bitherapy by lipid formulation of amphotericin B and posaconazole. The re-emergence and the high mortality of mucormycosis in solid organ transplant receiver show the necessity to find new therapeutic approaches. Posaconazole associated with liposomal amphotericin B could be an interesting option to treat disseminated mucormycosis and improve their outcome." @default.
• W2066490140 created "2016-06-24" @default.
• W2066490140 creator A5001373069 @default.
• W2066490140 creator A5006445470 @default.
• W2066490140 creator A5012692234 @default.
• W2066490140 creator A5013880694 @default.
• W2066490140 creator A5015745733 @default.
• W2066490140 creator A5026419711 @default.
• W2066490140 creator A5039514260 @default.
• W2066490140 creator A5041529206 @default.
• W2066490140 creator A5057058749 @default.
• W2066490140 creator A5057456447 @default.
• W2066490140 creator A5066349398 @default.
• W2066490140 creator A5075573725 @default.
• W2066490140 date "2009-11-01" @default.
• W2066490140 modified "2023-10-17" @default.
• W2066490140 title "Mucormycose disséminée d’évolution favorable chez une greffée pulmonaire" @default.
• W2066490140 cites W2013591045 @default.
• W2066490140 cites W2017219739 @default.
• W2066490140 cites W2100096120 @default.
• W2066490140 cites W2108597723 @default.
• W2066490140 cites W2142619354 @default.
• W2066490140 cites W2155809016 @default.
• W2066490140 cites W2161467702 @default.
• W2066490140 cites W2173265143 @default.
• W2066490140 cites W2986408534 @default.
• W2066490140 doi "https://doi.org/10.1016/s0761-8425(09)73337-6" @default.
• W2066490140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19953048" @default.
• W2066490140 hasPublicationYear "2009" @default.
• W2066490140 type Work @default.
• W2066490140 sameAs 2066490140 @default.
• W2066490140 citedByCount "5" @default.
• W2066490140 countsByYear W20664901402012 @default.
• W2066490140 countsByYear W20664901402013 @default.
• W2066490140 countsByYear W20664901402014 @default.
• W2066490140 countsByYear W20664901402020 @default.
• W2066490140 crossrefType "journal-article" @default.
• W2066490140 hasAuthorship W2066490140A5001373069 @default.
• W2066490140 hasAuthorship W2066490140A5006445470 @default.
• W2066490140 hasAuthorship W2066490140A5012692234 @default.
• W2066490140 hasAuthorship W2066490140A5013880694 @default.
• W2066490140 hasAuthorship W2066490140A5015745733 @default.
• W2066490140 hasAuthorship W2066490140A5026419711 @default.
• W2066490140 hasAuthorship W2066490140A5039514260 @default.
• W2066490140 hasAuthorship W2066490140A5041529206 @default.
• W2066490140 hasAuthorship W2066490140A5057058749 @default.
• W2066490140 hasAuthorship W2066490140A5057456447 @default.
• W2066490140 hasAuthorship W2066490140A5066349398 @default.
• W2066490140 hasAuthorship W2066490140A5075573725 @default.
• W2066490140 hasConcept C126322002 @default.
• W2066490140 hasConcept C141071460 @default.
• W2066490140 hasConcept C2776178081 @default.
• W2066490140 hasConcept C2777292849 @default.
• W2066490140 hasConcept C2777714996 @default.
• W2066490140 hasConcept C29456083 @default.
• W2066490140 hasConcept C2983914783 @default.
• W2066490140 hasConcept C71924100 @default.
• W2066490140 hasConceptScore W2066490140C126322002 @default.
• W2066490140 hasConceptScore W2066490140C141071460 @default.
• W2066490140 hasConceptScore W2066490140C2776178081 @default.
• W2066490140 hasConceptScore W2066490140C2777292849 @default.
• W2066490140 hasConceptScore W2066490140C2777714996 @default.
• W2066490140 hasConceptScore W2066490140C29456083 @default.
• W2066490140 hasConceptScore W2066490140C2983914783 @default.
• W2066490140 hasConceptScore W2066490140C71924100 @default.
• W2066490140 hasIssue "9" @default.
• W2066490140 hasLocation W20664901401 @default.
• W2066490140 hasLocation W20664901402 @default.
• W2066490140 hasOpenAccess W2066490140 @default.
• W2066490140 hasPrimaryLocation W20664901401 @default.
• W2066490140 hasRelatedWork W2025731178 @default.
• W2066490140 hasRelatedWork W2406705449 @default.
• W2066490140 hasRelatedWork W2517401272 @default.
• W2066490140 hasRelatedWork W2572725355 @default.
• W2066490140 hasRelatedWork W2572899577 @default.
• W2066490140 hasRelatedWork W2791232526 @default.
• W2066490140 hasRelatedWork W2908504074 @default.
• W2066490140 hasRelatedWork W67032640 @default.
• W2066490140 hasRelatedWork W2958451114 @default.
• W2066490140 hasRelatedWork W2992312071 @default.
• W2066490140 hasVolume "26" @default.
• W2066490140 isParatext "false" @default.
• W2066490140 isRetracted "false" @default.
• W2066490140 magId "2066490140" @default.
• W2066490140 workType "article" @default.