Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066572081> ?p ?o ?g. }
- W2066572081 abstract "Drug-eluting stents have a significant clinical advantage in late-stage restenosis due to the antiproliferative drug release. Understanding how drug transport occurs between coronary arterial locations can better help guide localized drug treatment options. Finite element models with properties from specific porcine coronary artery sections (left anterior descending (LAD), right (RCA); proximal, middle, distal regions) were created for stent deployment and drug delivery simulations. Stress, strain, pore fluid velocity, and drug concentrations were exported at different time points of simulation (0–180 days). Tests indicated that the highest stresses occurred in LAD sections. Higher-than-resting homeostatic levels of stress and strain existed at upwards of 3.0 mm away from the stented region, whereas concentration of species only reached 2.7 mm away from the stented region. Region-specific concentration showed 2.2 times higher concentrations in RCA artery sections at times corresponding to vascular remodeling (peak in the middle segment) compared to all other segments. These results suggest that wall transport can occur differently based on coronary artery location. Awareness of peak growth stimulators and where drug accumulation occurs in the vasculature can better help guide local drug delivery therapies." @default.
- W2066572081 created "2016-06-24" @default.
- W2066572081 creator A5027516722 @default.
- W2066572081 creator A5062110792 @default.
- W2066572081 creator A5077272194 @default.
- W2066572081 date "2013-05-09" @default.
- W2066572081 modified "2023-09-23" @default.
- W2066572081 title "A Finite Element Study on Variations in Mass Transport in Stented Porcine Coronary Arteries Based on Location in the Coronary Arterial Tree" @default.
- W2066572081 cites W1624164879 @default.
- W2066572081 cites W1963578344 @default.
- W2066572081 cites W1963884754 @default.
- W2066572081 cites W1980439584 @default.
- W2066572081 cites W1981386994 @default.
- W2066572081 cites W1981576281 @default.
- W2066572081 cites W1984514579 @default.
- W2066572081 cites W1984991382 @default.
- W2066572081 cites W1988193502 @default.
- W2066572081 cites W2006357156 @default.
- W2066572081 cites W2015795870 @default.
- W2066572081 cites W2017157577 @default.
- W2066572081 cites W2017919038 @default.
- W2066572081 cites W2020346958 @default.
- W2066572081 cites W2023129450 @default.
- W2066572081 cites W2026104001 @default.
- W2066572081 cites W2029288510 @default.
- W2066572081 cites W2030354697 @default.
- W2066572081 cites W2035277846 @default.
- W2066572081 cites W2044881528 @default.
- W2066572081 cites W2045601635 @default.
- W2066572081 cites W2046556105 @default.
- W2066572081 cites W2050910931 @default.
- W2066572081 cites W2053467994 @default.
- W2066572081 cites W2057556739 @default.
- W2066572081 cites W2060622258 @default.
- W2066572081 cites W2071827206 @default.
- W2066572081 cites W2076509587 @default.
- W2066572081 cites W2078804451 @default.
- W2066572081 cites W2082807438 @default.
- W2066572081 cites W2084441409 @default.
- W2066572081 cites W2097531187 @default.
- W2066572081 cites W2099167181 @default.
- W2066572081 cites W2108871285 @default.
- W2066572081 cites W2110036880 @default.
- W2066572081 cites W2119295078 @default.
- W2066572081 cites W2123480020 @default.
- W2066572081 cites W2135820925 @default.
- W2066572081 cites W2139397108 @default.
- W2066572081 cites W2144762496 @default.
- W2066572081 cites W2153535413 @default.
- W2066572081 cites W2163973529 @default.
- W2066572081 cites W2548966800 @default.
- W2066572081 doi "https://doi.org/10.1115/1.4024137" @default.
- W2066572081 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5413126" @default.
- W2066572081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23699720" @default.
- W2066572081 hasPublicationYear "2013" @default.
- W2066572081 type Work @default.
- W2066572081 sameAs 2066572081 @default.
- W2066572081 citedByCount "3" @default.
- W2066572081 countsByYear W20665720812016 @default.
- W2066572081 countsByYear W20665720812017 @default.
- W2066572081 countsByYear W20665720812020 @default.
- W2066572081 crossrefType "journal-article" @default.
- W2066572081 hasAuthorship W2066572081A5027516722 @default.
- W2066572081 hasAuthorship W2066572081A5062110792 @default.
- W2066572081 hasAuthorship W2066572081A5077272194 @default.
- W2066572081 hasBestOaLocation W20665720812 @default.
- W2066572081 hasConcept C126322002 @default.
- W2066572081 hasConcept C164705383 @default.
- W2066572081 hasConcept C2776619873 @default.
- W2066572081 hasConcept C2776820930 @default.
- W2066572081 hasConcept C2777546689 @default.
- W2066572081 hasConcept C2778283817 @default.
- W2066572081 hasConcept C2778583881 @default.
- W2066572081 hasConcept C2778742706 @default.
- W2066572081 hasConcept C71924100 @default.
- W2066572081 hasConceptScore W2066572081C126322002 @default.
- W2066572081 hasConceptScore W2066572081C164705383 @default.
- W2066572081 hasConceptScore W2066572081C2776619873 @default.
- W2066572081 hasConceptScore W2066572081C2776820930 @default.
- W2066572081 hasConceptScore W2066572081C2777546689 @default.
- W2066572081 hasConceptScore W2066572081C2778283817 @default.
- W2066572081 hasConceptScore W2066572081C2778583881 @default.
- W2066572081 hasConceptScore W2066572081C2778742706 @default.
- W2066572081 hasConceptScore W2066572081C71924100 @default.
- W2066572081 hasIssue "6" @default.
- W2066572081 hasLocation W20665720811 @default.
- W2066572081 hasLocation W20665720812 @default.
- W2066572081 hasLocation W20665720813 @default.
- W2066572081 hasLocation W20665720814 @default.
- W2066572081 hasOpenAccess W2066572081 @default.
- W2066572081 hasPrimaryLocation W20665720811 @default.
- W2066572081 hasRelatedWork W1502204200 @default.
- W2066572081 hasRelatedWork W1982033681 @default.
- W2066572081 hasRelatedWork W2040400039 @default.
- W2066572081 hasRelatedWork W2045862920 @default.
- W2066572081 hasRelatedWork W2066572081 @default.
- W2066572081 hasRelatedWork W2379623550 @default.
- W2066572081 hasRelatedWork W2413083139 @default.
- W2066572081 hasRelatedWork W2980572013 @default.
- W2066572081 hasRelatedWork W3020488790 @default.