FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066600997> ?p ?o ?g. }

• W2066600997 abstract "This study was designed to identify a dose of alprazolam that would reduce anxiety associated with oral surgery without causing accompanying memory impairment.Thirty-six subjects in experiment 1 and 48 subjects in experiment 2 were pretested on a computerized memory battery to establish baseline performance. Subjects were then randomly assigned to receive placebo, 0.25 mg, or 0.75 mg oral alprazolam (experiment 1) or placebo, 0.25 mg, 0.50 mg, or 0.75 mg oral alprazolam (experiment 2). Forty-five minutes after the double-blind administration of alprazolam, subjects were given a second memory battery. The memory batteries tested story recall and recognition and word recall and recognition. Subjects in experiment 2 subsequently underwent oral surgery for the removal of one to four molars. The subjects completed anxiety questionnaires both before and after surgery.The 0.75-mg and 0.50-mg doses, but not the 0.25-mg dose, impaired word recall. The 0.75-mg dose also impaired story recall and recognition. The proportion of subjects reporting moderate to high anxiety during oral surgery decreased with increasing doses of alprazolam. Multiple regression indicated that the 0.75-mg alprazolam dose significantly decreased anxiety during oral surgery. The 0.25-mg and 0.50-mg doses also tended to reduce anxiety, but beta values for these doses did not reach significance.These findings indicate that alprazolam produces memory impairment at the dosages necessary to produce clinically significant anxiolysis during oral surgery." @default.
• W2066600997 created "2016-06-24" @default.
• W2066600997 creator A5006178504 @default.
• W2066600997 creator A5033205116 @default.
• W2066600997 creator A5038964670 @default.
• W2066600997 creator A5048318378 @default.
• W2066600997 date "1997-10-01" @default.
• W2066600997 modified "2023-09-23" @default.
• W2066600997 title "Amnestic and anxiolytic effects of alprazolam in oral surgery patients" @default.
• W2066600997 cites W1913030039 @default.
• W2066600997 cites W1965225694 @default.
• W2066600997 cites W1967054145 @default.
• W2066600997 cites W1968044676 @default.
• W2066600997 cites W1979786250 @default.
• W2066600997 cites W1980969992 @default.
• W2066600997 cites W1981137488 @default.
• W2066600997 cites W1983502257 @default.
• W2066600997 cites W1993381432 @default.
• W2066600997 cites W2002833028 @default.
• W2066600997 cites W2021206815 @default.
• W2066600997 cites W2032083307 @default.
• W2066600997 cites W2048786655 @default.
• W2066600997 cites W2068717335 @default.
• W2066600997 cites W2072239196 @default.
• W2066600997 cites W2073266088 @default.
• W2066600997 cites W2077536772 @default.
• W2066600997 cites W2089458551 @default.
• W2066600997 cites W2100773442 @default.
• W2066600997 cites W2115622198 @default.
• W2066600997 cites W2133569755 @default.
• W2066600997 cites W2143305149 @default.
• W2066600997 cites W2316732338 @default.
• W2066600997 cites W4237643387 @default.
• W2066600997 cites W4238079920 @default.
• W2066600997 cites W4301806771 @default.
• W2066600997 doi "https://doi.org/10.1016/s0278-2391(97)90280-9" @default.
• W2066600997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9331228" @default.
• W2066600997 hasPublicationYear "1997" @default.
• W2066600997 type Work @default.
• W2066600997 sameAs 2066600997 @default.
• W2066600997 citedByCount "20" @default.
• W2066600997 countsByYear W20666009972012 @default.
• W2066600997 countsByYear W20666009972015 @default.
• W2066600997 countsByYear W20666009972021 @default.
• W2066600997 crossrefType "journal-article" @default.
• W2066600997 hasAuthorship W2066600997A5006178504 @default.
• W2066600997 hasAuthorship W2066600997A5033205116 @default.
• W2066600997 hasAuthorship W2066600997A5038964670 @default.
• W2066600997 hasAuthorship W2066600997A5048318378 @default.
• W2066600997 hasConcept C100660578 @default.
• W2066600997 hasConcept C118552586 @default.
• W2066600997 hasConcept C126322002 @default.
• W2066600997 hasConcept C142724271 @default.
• W2066600997 hasConcept C15744967 @default.
• W2066600997 hasConcept C162156334 @default.
• W2066600997 hasConcept C180747234 @default.
• W2066600997 hasConcept C204787440 @default.
• W2066600997 hasConcept C27081682 @default.
• W2066600997 hasConcept C2777056448 @default.
• W2066600997 hasConcept C2777196872 @default.
• W2066600997 hasConcept C2777765862 @default.
• W2066600997 hasConcept C2778300832 @default.
• W2066600997 hasConcept C2779706987 @default.
• W2066600997 hasConcept C42219234 @default.
• W2066600997 hasConcept C558461103 @default.
• W2066600997 hasConcept C71924100 @default.
• W2066600997 hasConceptScore W2066600997C100660578 @default.
• W2066600997 hasConceptScore W2066600997C118552586 @default.
• W2066600997 hasConceptScore W2066600997C126322002 @default.
• W2066600997 hasConceptScore W2066600997C142724271 @default.
• W2066600997 hasConceptScore W2066600997C15744967 @default.
• W2066600997 hasConceptScore W2066600997C162156334 @default.
• W2066600997 hasConceptScore W2066600997C180747234 @default.
• W2066600997 hasConceptScore W2066600997C204787440 @default.
• W2066600997 hasConceptScore W2066600997C27081682 @default.
• W2066600997 hasConceptScore W2066600997C2777056448 @default.
• W2066600997 hasConceptScore W2066600997C2777196872 @default.
• W2066600997 hasConceptScore W2066600997C2777765862 @default.
• W2066600997 hasConceptScore W2066600997C2778300832 @default.
• W2066600997 hasConceptScore W2066600997C2779706987 @default.
• W2066600997 hasConceptScore W2066600997C42219234 @default.
• W2066600997 hasConceptScore W2066600997C558461103 @default.
• W2066600997 hasConceptScore W2066600997C71924100 @default.
• W2066600997 hasLocation W20666009971 @default.
• W2066600997 hasLocation W20666009972 @default.
• W2066600997 hasOpenAccess W2066600997 @default.
• W2066600997 hasPrimaryLocation W20666009971 @default.
• W2066600997 hasRelatedWork W1526955680 @default.
• W2066600997 hasRelatedWork W1841008104 @default.
• W2066600997 hasRelatedWork W1964821470 @default.
• W2066600997 hasRelatedWork W1974843915 @default.
• W2066600997 hasRelatedWork W1976096830 @default.
• W2066600997 hasRelatedWork W2017857758 @default.
• W2066600997 hasRelatedWork W2056068291 @default.
• W2066600997 hasRelatedWork W2066600997 @default.
• W2066600997 hasRelatedWork W2095019566 @default.
• W2066600997 hasRelatedWork W2410678083 @default.
• W2066600997 isParatext "false" @default.
• W2066600997 isRetracted "false" @default.
• W2066600997 magId "2066600997" @default.

• next