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- W2066601257 abstract "The study shows that serum from pneumococcal polysaccharide type III (SSSIII)-immunized and nonimmunized mice that has been absorbed until devoid of anti-SSSIII antibodies inhibits anti-SSSIII plaque-forming cells (PFC) but not antisheep red blood PFC in antibody plaque assay. A large fraction of the inhibitions activity can be absorbed by and eluted from anti-SSSIII-Sepharose, but not normal mouse serum-Sepharose. It has low or no affinity for protein A and concanavalin A. The titre of the inhibitor increases with repeated immunizations and inhibits the anti-SSSIII PFC of rats or mice of different allotypes. On the basis of these characteristics, I classify the inhibitor as an anti-idiotypic nonimmunoglobulin factor directed against a common determinant of anti-SSSIII antibodies of mouse and rat, with an immuno-regulatory function." @default.
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- W2066601257 date "1986-03-01" @default.
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- W2066601257 title "The Immune Response to Pneumococcal Polysaccharide Type III is Followed by Increased Production of an Antibody Antifactor" @default.
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- W2066601257 doi "https://doi.org/10.1111/j.1365-3083.1986.tb01972.x" @default.
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