FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066621833> ?p ?o ?g. }

• W2066621833 endingPage "7" @default.
• W2066621833 startingPage "1" @default.
• W2066621833 abstract "Disrupted sleep is prevalent in both mood and thyroid disorders. Given the emerging use of thyroid hormones in the treatment of mood disorders, we investigated the effects of supraphysiological doses of levothyroxine (L-T4) on sleep. In an open-label design, 13 healthy subjects received up to 500 μ g/day for an eight-week period. A baseline night was polysomnographically recorded (PSG) followed by PSG under the maximum tolerated dose of L-T4. All subjects developed hyperthyroxinemia. The heart rate and respiration rate increased significantly with treatment; a significant increase in body temperature was observed in men but not in women. Surprisingly, treatment with supraphysiological doses of L-T4 did not cause significant effects on sleep architecture. However, the increase in body movements and REM density was close to reaching statistical significance. Here, we report on the sleep data, thyroid hormone levels, and physiological parameters during sleep. We conclude that experimentally induced hyperthyroidism does not profoundly change the sleep structure in healthy individuals underlining the good tolerability of treatment with supraphysiological doses of L-T4 in patients with mood disorders." @default.
• W2066621833 created "2016-06-24" @default.
• W2066621833 creator A5007352854 @default.
• W2066621833 creator A5041397944 @default.
• W2066621833 creator A5044183101 @default.
• W2066621833 creator A5045231235 @default.
• W2066621833 creator A5073883544 @default.
• W2066621833 date "2011-01-01" @default.
• W2066621833 modified "2023-10-01" @default.
• W2066621833 title "Effects of Supraphysiological Doses of Levothyroxine on Sleep in Healthy Subjects: A Prospective Polysomnography Study" @default.
• W2066621833 cites W1965887699 @default.
• W2066621833 cites W1972513346 @default.
• W2066621833 cites W1977398830 @default.
• W2066621833 cites W1983139854 @default.
• W2066621833 cites W1984161074 @default.
• W2066621833 cites W1997526715 @default.
• W2066621833 cites W1997784404 @default.
• W2066621833 cites W2007867862 @default.
• W2066621833 cites W2012173637 @default.
• W2066621833 cites W2031560695 @default.
• W2066621833 cites W2035148491 @default.
• W2066621833 cites W2056752893 @default.
• W2066621833 cites W2060446870 @default.
• W2066621833 cites W2063633162 @default.
• W2066621833 cites W2068366212 @default.
• W2066621833 cites W2090408673 @default.
• W2066621833 cites W2095355308 @default.
• W2066621833 cites W2102065055 @default.
• W2066621833 cites W2102934296 @default.
• W2066621833 cites W2118954082 @default.
• W2066621833 cites W2120767466 @default.
• W2066621833 cites W2126376525 @default.
• W2066621833 cites W2162391320 @default.
• W2066621833 cites W2167231164 @default.
• W2066621833 cites W2168933702 @default.
• W2066621833 cites W2338388603 @default.
• W2066621833 doi "https://doi.org/10.4061/2011/420580" @default.
• W2066621833 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3134320" @default.
• W2066621833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21765990" @default.
• W2066621833 hasPublicationYear "2011" @default.
• W2066621833 type Work @default.
• W2066621833 sameAs 2066621833 @default.
• W2066621833 citedByCount "11" @default.
• W2066621833 countsByYear W20666218332014 @default.
• W2066621833 countsByYear W20666218332016 @default.
• W2066621833 countsByYear W20666218332017 @default.
• W2066621833 countsByYear W20666218332018 @default.
• W2066621833 countsByYear W20666218332019 @default.
• W2066621833 countsByYear W20666218332020 @default.
• W2066621833 countsByYear W20666218332021 @default.
• W2066621833 countsByYear W20666218332022 @default.
• W2066621833 crossrefType "journal-article" @default.
• W2066621833 hasAuthorship W2066621833A5007352854 @default.
• W2066621833 hasAuthorship W2066621833A5041397944 @default.
• W2066621833 hasAuthorship W2066621833A5044183101 @default.
• W2066621833 hasAuthorship W2066621833A5045231235 @default.
• W2066621833 hasAuthorship W2066621833A5073883544 @default.
• W2066621833 hasBestOaLocation W20666218331 @default.
• W2066621833 hasConcept C111919701 @default.
• W2066621833 hasConcept C118552586 @default.
• W2066621833 hasConcept C126322002 @default.
• W2066621833 hasConcept C134018914 @default.
• W2066621833 hasConcept C197934379 @default.
• W2066621833 hasConcept C2775841894 @default.
• W2066621833 hasConcept C2775883008 @default.
• W2066621833 hasConcept C2778205975 @default.
• W2066621833 hasConcept C2778375690 @default.
• W2066621833 hasConcept C2780733359 @default.
• W2066621833 hasConcept C2781326671 @default.
• W2066621833 hasConcept C41008148 @default.
• W2066621833 hasConcept C526584372 @default.
• W2066621833 hasConcept C71315377 @default.
• W2066621833 hasConcept C71924100 @default.
• W2066621833 hasConceptScore W2066621833C111919701 @default.
• W2066621833 hasConceptScore W2066621833C118552586 @default.
• W2066621833 hasConceptScore W2066621833C126322002 @default.
• W2066621833 hasConceptScore W2066621833C134018914 @default.
• W2066621833 hasConceptScore W2066621833C197934379 @default.
• W2066621833 hasConceptScore W2066621833C2775841894 @default.
• W2066621833 hasConceptScore W2066621833C2775883008 @default.
• W2066621833 hasConceptScore W2066621833C2778205975 @default.
• W2066621833 hasConceptScore W2066621833C2778375690 @default.
• W2066621833 hasConceptScore W2066621833C2780733359 @default.
• W2066621833 hasConceptScore W2066621833C2781326671 @default.
• W2066621833 hasConceptScore W2066621833C41008148 @default.
• W2066621833 hasConceptScore W2066621833C526584372 @default.
• W2066621833 hasConceptScore W2066621833C71315377 @default.
• W2066621833 hasConceptScore W2066621833C71924100 @default.
• W2066621833 hasLocation W20666218331 @default.
• W2066621833 hasLocation W20666218332 @default.
• W2066621833 hasLocation W20666218333 @default.
• W2066621833 hasLocation W20666218334 @default.
• W2066621833 hasLocation W20666218335 @default.
• W2066621833 hasOpenAccess W2066621833 @default.
• W2066621833 hasPrimaryLocation W20666218331 @default.
• W2066621833 hasRelatedWork W117621442 @default.
• W2066621833 hasRelatedWork W2009526181 @default.
• W2066621833 hasRelatedWork W2010645160 @default.

• next