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- W2066654312 abstract "The active exogenous murine leukemia virus sequences of mouse cells growing in culture are preferentially digested by deoxyribonuclease I in metaphase chromosomes. As determined by nuclear nick translation, all of the gene sequences of these cells active during interphase are in a deoxyribonuclease I-sensitive conformation during metaphase. This method of nick translation can therefore be used to label chromosomes in situ in order to visualize the active regions of the genome." @default.
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- W2066654312 date "1982-08-13" @default.
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- W2066654312 title "Active Genes Are Sensitive to Deoxyribonuclease I During Metaphase" @default.
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- W2066654312 doi "https://doi.org/10.1126/science.6283640" @default.
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