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- W2066673556 abstract "Abstract A method is described to obtain intracerebral self‐stimulation in the goat. Permanent platinum iridium electrodes were implanted into the hypothalamus. The animal could elicit the electrical stimuli by pressing a switch connected to a stimulator that delivered trains of damped square pulses to the electrodes. High rates of self‐stimulation were obtained in the premamillary region of the hypothalamus between columna fornices descendens and tractus mamillothalamicus. The behaviour of the goats during self‐stimulation was observed, as well as the different rates and frequencies of self‐stimulation that they developed at various electrode sites. The influence of different strengths of current on the rate of self‐stimulation was also observed. In some parts where high rates of self‐stimulation were obtained, an increase in current strength up to 1.0 mA did not decrease the rate of self‐stimulation. A sudden change to stimuli in “rewarding areas” that never before had been tested with electric current immediately developed high rates of self‐stimulation. Amphetamine was tested on self‐stimulating animals. The drug increased the animals' urge for self‐stimulation." @default.
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- W2066673556 date "1962-06-01" @default.
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- W2066673556 title "Self-Stimulation in the Goat" @default.
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- W2066673556 doi "https://doi.org/10.1111/j.1748-1716.1962.tb02441.x" @default.
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