Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066709903> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2066709903 endingPage "697" @default.
- W2066709903 startingPage "689" @default.
- W2066709903 abstract "The efficacy of a Tc99m-labeled anti-lymphoma antibody fragment, bectumomab [LymphoScan], was retrospectively examined in the staging of recurrent or newly diagnosed non-Hodgkin's lymphoma (NHL) [7 patients] and to assess targeting before radioimmunotherapy (RIT) [14 patients]. Performance was graded relative to conventional imaging. Tumors included 7 low-grade, 11 intermediate-grade, and 3 high-grade histologic subtypes. Computed x-ray tomography, radiogallium imaging, FDG-PET, and bone marrow biopsy defined 117 sites. Bectumomab revealed 56% of these sites. In 4 patients bectumomab uncovered five sites not evident by conventional imaging. In addition, it uncovered one site in the brain, an area not covered in the standard work-up of asymptomatic patients. Bectumomab imaging most often failed in central abdominal and thoracic locations, and excelled in revealing disease in the head and neck. Relative to Ga67 citrate imaging, the performance of bectumomab was variable, with no clear relation to anatomic location; there was better targeting of low and intermediate grade NHL. Radiogallium out-performed bectumomab imaging in 23 sites, 19 of which were in patients with high or intermediate-grade disease. Bectumomab was superior to radiogallium at six sites, five of which involved low-grade tumor.Bectumomab shows promise as a pre-RIT probe for targeting of B-cell NHL. It excelled at defining small volume, low-grade disease. However, as a purely diagnostic agent, its performance was variable." @default.
- W2066709903 created "2016-06-24" @default.
- W2066709903 creator A5002521084 @default.
- W2066709903 creator A5004299253 @default.
- W2066709903 creator A5025865972 @default.
- W2066709903 creator A5063420130 @default.
- W2066709903 creator A5078671245 @default.
- W2066709903 date "2002-12-01" @default.
- W2066709903 modified "2023-10-10" @default.
- W2066709903 title "Radioimmunoscintigraphy (RIS) with Bectumomab (Tc99m Labeled IMMU-LL2, Lymphoscan<sup>®</sup>) in the Assessment of Recurrent Non-Hodgkin's Lymphoma (NHL)" @default.
- W2066709903 cites W1951122501 @default.
- W2066709903 cites W1995965471 @default.
- W2066709903 cites W2007083365 @default.
- W2066709903 cites W2082136768 @default.
- W2066709903 cites W2168926834 @default.
- W2066709903 cites W2267583049 @default.
- W2066709903 cites W4252432886 @default.
- W2066709903 doi "https://doi.org/10.1089/108497802320970307" @default.
- W2066709903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12537673" @default.
- W2066709903 hasPublicationYear "2002" @default.
- W2066709903 type Work @default.
- W2066709903 sameAs 2066709903 @default.
- W2066709903 citedByCount "11" @default.
- W2066709903 countsByYear W20667099032013 @default.
- W2066709903 countsByYear W20667099032014 @default.
- W2066709903 countsByYear W20667099032015 @default.
- W2066709903 countsByYear W20667099032018 @default.
- W2066709903 crossrefType "journal-article" @default.
- W2066709903 hasAuthorship W2066709903A5002521084 @default.
- W2066709903 hasAuthorship W2066709903A5004299253 @default.
- W2066709903 hasAuthorship W2066709903A5025865972 @default.
- W2066709903 hasAuthorship W2066709903A5063420130 @default.
- W2066709903 hasAuthorship W2066709903A5078671245 @default.
- W2066709903 hasConcept C126838900 @default.
- W2066709903 hasConcept C142724271 @default.
- W2066709903 hasConcept C159654299 @default.
- W2066709903 hasConcept C203014093 @default.
- W2066709903 hasConcept C2775934546 @default.
- W2066709903 hasConcept C2776146153 @default.
- W2066709903 hasConcept C2777910003 @default.
- W2066709903 hasConcept C2779338263 @default.
- W2066709903 hasConcept C2989005 @default.
- W2066709903 hasConcept C542903549 @default.
- W2066709903 hasConcept C71924100 @default.
- W2066709903 hasConceptScore W2066709903C126838900 @default.
- W2066709903 hasConceptScore W2066709903C142724271 @default.
- W2066709903 hasConceptScore W2066709903C159654299 @default.
- W2066709903 hasConceptScore W2066709903C203014093 @default.
- W2066709903 hasConceptScore W2066709903C2775934546 @default.
- W2066709903 hasConceptScore W2066709903C2776146153 @default.
- W2066709903 hasConceptScore W2066709903C2777910003 @default.
- W2066709903 hasConceptScore W2066709903C2779338263 @default.
- W2066709903 hasConceptScore W2066709903C2989005 @default.
- W2066709903 hasConceptScore W2066709903C542903549 @default.
- W2066709903 hasConceptScore W2066709903C71924100 @default.
- W2066709903 hasIssue "6" @default.
- W2066709903 hasLocation W20667099031 @default.
- W2066709903 hasLocation W20667099032 @default.
- W2066709903 hasOpenAccess W2066709903 @default.
- W2066709903 hasPrimaryLocation W20667099031 @default.
- W2066709903 hasRelatedWork W1532568685 @default.
- W2066709903 hasRelatedWork W1787597555 @default.
- W2066709903 hasRelatedWork W1994649805 @default.
- W2066709903 hasRelatedWork W2001235000 @default.
- W2066709903 hasRelatedWork W2064812522 @default.
- W2066709903 hasRelatedWork W2066978337 @default.
- W2066709903 hasRelatedWork W2169294576 @default.
- W2066709903 hasRelatedWork W2386398244 @default.
- W2066709903 hasRelatedWork W2407024650 @default.
- W2066709903 hasRelatedWork W2945136554 @default.
- W2066709903 hasVolume "17" @default.
- W2066709903 isParatext "false" @default.
- W2066709903 isRetracted "false" @default.
- W2066709903 magId "2066709903" @default.
- W2066709903 workType "article" @default.