Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066730300> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2066730300 endingPage "458" @default.
- W2066730300 startingPage "451" @default.
- W2066730300 abstract "The combined gene protein assay (GPA) can simultaneously assess HER2 gene copy number and protein on a single slide using bright-field microscopy.GPA was compared with a fluorescence in situ hybridization (FISH) assay on 50 invasive breast carcinomas with a 2+ score on immunohistochemistry (IHC).The cases were categorized into positive, equivocal, or negative for HER2 gene amplification using the 2013 American Society of Clinical Oncology/College of American Pathologists criteria. This resulted in 82% agreement (41 of 50) between FISH and GPA. In addition, 25 known IHC 3+ breast carcinomas analyzed by GPA showed protein overexpression and clusters of HER2 gene consistent with unequivocal amplification, and 22 known IHC-negative cases were negative for HER2 gene amplification by GPA.Although GPA is an alternative to both IHC and FISH, it may be an unnecessary test for IHC 0/1+/3+ cases. The clinical utility of GPA appears to be similar to other in situ hybridization assays (ie, adjudicator of HER2 status for IHC 2+ cases)." @default.
- W2066730300 created "2016-06-24" @default.
- W2066730300 creator A5005474369 @default.
- W2066730300 creator A5027957798 @default.
- W2066730300 creator A5034149172 @default.
- W2066730300 creator A5085410951 @default.
- W2066730300 date "2015-03-01" @default.
- W2066730300 modified "2023-10-01" @default.
- W2066730300 title "Dual HER2 Gene Protein Assay" @default.
- W2066730300 cites W1974618724 @default.
- W2066730300 cites W1976545696 @default.
- W2066730300 cites W1995215272 @default.
- W2066730300 cites W1995966265 @default.
- W2066730300 cites W1997056190 @default.
- W2066730300 cites W2020472322 @default.
- W2066730300 cites W2039428606 @default.
- W2066730300 cites W2043905676 @default.
- W2066730300 cites W2048815504 @default.
- W2066730300 cites W2051764918 @default.
- W2066730300 cites W2052244202 @default.
- W2066730300 cites W2090050157 @default.
- W2066730300 cites W2101979288 @default.
- W2066730300 cites W2108161018 @default.
- W2066730300 cites W2114672052 @default.
- W2066730300 cites W2130900820 @default.
- W2066730300 cites W2131775652 @default.
- W2066730300 cites W2137840817 @default.
- W2066730300 cites W2156500288 @default.
- W2066730300 cites W2156677665 @default.
- W2066730300 cites W2157524247 @default.
- W2066730300 cites W2162864375 @default.
- W2066730300 cites W2164325465 @default.
- W2066730300 doi "https://doi.org/10.1309/ajcpkivvw4obpx6i" @default.
- W2066730300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25696805" @default.
- W2066730300 hasPublicationYear "2015" @default.
- W2066730300 type Work @default.
- W2066730300 sameAs 2066730300 @default.
- W2066730300 citedByCount "12" @default.
- W2066730300 countsByYear W20667303002016 @default.
- W2066730300 countsByYear W20667303002017 @default.
- W2066730300 countsByYear W20667303002018 @default.
- W2066730300 countsByYear W20667303002019 @default.
- W2066730300 countsByYear W20667303002020 @default.
- W2066730300 countsByYear W20667303002023 @default.
- W2066730300 crossrefType "journal-article" @default.
- W2066730300 hasAuthorship W2066730300A5005474369 @default.
- W2066730300 hasAuthorship W2066730300A5027957798 @default.
- W2066730300 hasAuthorship W2066730300A5034149172 @default.
- W2066730300 hasAuthorship W2066730300A5085410951 @default.
- W2066730300 hasConcept C104317684 @default.
- W2066730300 hasConcept C142724271 @default.
- W2066730300 hasConcept C150194340 @default.
- W2066730300 hasConcept C153911025 @default.
- W2066730300 hasConcept C204232928 @default.
- W2066730300 hasConcept C2777542201 @default.
- W2066730300 hasConcept C2909208804 @default.
- W2066730300 hasConcept C30481170 @default.
- W2066730300 hasConcept C505870484 @default.
- W2066730300 hasConcept C54355233 @default.
- W2066730300 hasConcept C71924100 @default.
- W2066730300 hasConcept C7602840 @default.
- W2066730300 hasConcept C81439078 @default.
- W2066730300 hasConcept C86803240 @default.
- W2066730300 hasConceptScore W2066730300C104317684 @default.
- W2066730300 hasConceptScore W2066730300C142724271 @default.
- W2066730300 hasConceptScore W2066730300C150194340 @default.
- W2066730300 hasConceptScore W2066730300C153911025 @default.
- W2066730300 hasConceptScore W2066730300C204232928 @default.
- W2066730300 hasConceptScore W2066730300C2777542201 @default.
- W2066730300 hasConceptScore W2066730300C2909208804 @default.
- W2066730300 hasConceptScore W2066730300C30481170 @default.
- W2066730300 hasConceptScore W2066730300C505870484 @default.
- W2066730300 hasConceptScore W2066730300C54355233 @default.
- W2066730300 hasConceptScore W2066730300C71924100 @default.
- W2066730300 hasConceptScore W2066730300C7602840 @default.
- W2066730300 hasConceptScore W2066730300C81439078 @default.
- W2066730300 hasConceptScore W2066730300C86803240 @default.
- W2066730300 hasIssue "3" @default.
- W2066730300 hasLocation W20667303001 @default.
- W2066730300 hasLocation W20667303002 @default.
- W2066730300 hasOpenAccess W2066730300 @default.
- W2066730300 hasPrimaryLocation W20667303001 @default.
- W2066730300 hasRelatedWork W1988833950 @default.
- W2066730300 hasRelatedWork W2009966535 @default.
- W2066730300 hasRelatedWork W2044791827 @default.
- W2066730300 hasRelatedWork W2111721589 @default.
- W2066730300 hasRelatedWork W2111981527 @default.
- W2066730300 hasRelatedWork W2113645643 @default.
- W2066730300 hasRelatedWork W2352385085 @default.
- W2066730300 hasRelatedWork W2373480787 @default.
- W2066730300 hasRelatedWork W2386508380 @default.
- W2066730300 hasRelatedWork W2927714659 @default.
- W2066730300 hasVolume "143" @default.
- W2066730300 isParatext "false" @default.
- W2066730300 isRetracted "false" @default.
- W2066730300 magId "2066730300" @default.
- W2066730300 workType "article" @default.