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- W2066745218 abstract "Abstract It is well known that hydrotropes have a very high minimum hydrotrope concentration (MHC), posing a question on their applications. We have found that MHC (obtained by conductivity and surface tension measurements) can be reduced by the addition of foreign materials. The association tendency can be improved by the addition of salts, n ‐alkanols, and ureas. Urea decreases or increases the MHC depending on whether the urea content is lower or higher (e.g., the increased solubility of sparingly soluble riboflavin corroborates the increase in the hydrotropic properties of the system). In the present work, the association tendencies of sodium salicylate (a well‐known hydrotrope), sodium dodecyl sulfate, and sodium bromide were compared. The results have direct implications in the mechanism of protein denaturation and may provide insight into the role of urea in supramolecular assemblies." @default.
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- W2066745218 date "2005-01-01" @default.
- W2066745218 modified "2023-09-29" @default.
- W2066745218 title "Additive-induced association in unconventional systems: A case of the hydrotrope" @default.
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- W2066745218 doi "https://doi.org/10.1007/s11743-005-0338-2" @default.
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