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• W2066871851 abstract "A novel cardio-excitatory peptide was purified from the hearts of Aplysia kurodai. The peptide was a tripeptide containing a D-amino acid residue in the second position, Asn-D-Trp-Phe-NH2 (NdWFamide). NdWFamide increased the amplitude of contractions of the perfused Aplysia heart with little effect on beating frequency, showing a threshold of approximately 10(-11) M. The peptide also potentiated spontaneous contractions of the anterior aorta. The synthetic peptide having L-Trp instead of D-Trp was about 1,000 times less potent than the native one. NdWFamide seems to play an important role in regulation of cardiac activity in Aplysia." @default.
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• W2066871851 date "1997-11-01" @default.
• W2066871851 modified "2023-09-26" @default.
• W2066871851 title "A Noveld-Amino-Acid-Containing Peptide Isolated fromAplysiaHeart" @default.
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• W2066871851 doi "https://doi.org/10.1006/bbrc.1997.7659" @default.
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