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- W2066884297 abstract "Wavefront distortion fundamentally limits the achievable imaging depth and quality in thick tissue. Wavefront correction can help restore the diffraction limited focus albeit with a small field of view (FOV), which limits its imaging applications. In this work, we numerically investigate whether the multi-conjugate configuration, originally developed for astronomical adaptive optics, may increase the correction FOV in random turbid media. The results show that the multi-conjugate configuration can significantly improve the correction area compared to the widely adopted pupil plane correction. Even in the simple case of single-conjugation, it still outperforms the pupil plane correction. This study provides a guideline for designing the optimal wavefront correction system in deep tissue imaging." @default.
- W2066884297 created "2016-06-24" @default.
- W2066884297 creator A5009941503 @default.
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- W2066884297 date "2015-03-13" @default.
- W2066884297 modified "2023-09-24" @default.
- W2066884297 title "Numerical study of multi-conjugate large area wavefront correction for deep tissue microscopy" @default.
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- W2066884297 doi "https://doi.org/10.1364/oe.23.007463" @default.
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