Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066895159> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2066895159 endingPage "1001" @default.
- W2066895159 startingPage "993" @default.
- W2066895159 abstract "Yin Chen Hao Tang preparation (YCHTP) is a classic traditional Chinese medicine formula, which is commonly used for clinical treatment of hepatological diseases. In this study, a rapid and validated high-performance liquid chromatography (HPLC) method was developed to simultaneously identify 6,7-dimethylesculetin and geniposide in rat plasma. This assay was performed on a Dikma Diamonsil RP(18) column (200 mm×4.6 mm, 5 μm) with acetonitrile-methanol-water (0.1% formic acid) as the mobile phase, showing acceptable linearity, intra- and inter-day precision and accuracy (R.S.D.=5%), and absolute recovery for two analytes (74%); the limits of quantitation were 0.4 and 1.12 μg/ml, and the limits of detection were 0.06 and 0.09 μg/ml for two analytes. The developed method was successfully applied to study the effect of formula compatibility on the pharmacokinetics of 6,7-dimethylesculetin and geniposide in YCHTP when orally administrating an effective human daily dose of YCHTP to rats. We surmise that formula compatibility can significantly influence the pharmacokinetics of YCHTP, and we have elucidated and validated the compatible administration of YCHTP." @default.
- W2066895159 created "2016-06-24" @default.
- W2066895159 creator A5007105396 @default.
- W2066895159 creator A5020597164 @default.
- W2066895159 creator A5028774110 @default.
- W2066895159 creator A5032415345 @default.
- W2066895159 creator A5066808555 @default.
- W2066895159 creator A5067443541 @default.
- W2066895159 creator A5084687544 @default.
- W2066895159 date "2008-11-01" @default.
- W2066895159 modified "2023-09-30" @default.
- W2066895159 title "Pharmacokinetic studies of a Chinese triple herbal drug formula" @default.
- W2066895159 cites W1964567968 @default.
- W2066895159 cites W1992014852 @default.
- W2066895159 cites W1996753533 @default.
- W2066895159 cites W2028157997 @default.
- W2066895159 cites W2033144782 @default.
- W2066895159 cites W2039192544 @default.
- W2066895159 cites W2044499795 @default.
- W2066895159 cites W2049356744 @default.
- W2066895159 cites W2053137841 @default.
- W2066895159 cites W2053680606 @default.
- W2066895159 cites W2081199043 @default.
- W2066895159 cites W2083407540 @default.
- W2066895159 cites W2170654708 @default.
- W2066895159 cites W2412891257 @default.
- W2066895159 doi "https://doi.org/10.1016/j.phymed.2008.01.006" @default.
- W2066895159 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18339526" @default.
- W2066895159 hasPublicationYear "2008" @default.
- W2066895159 type Work @default.
- W2066895159 sameAs 2066895159 @default.
- W2066895159 citedByCount "28" @default.
- W2066895159 countsByYear W20668951592012 @default.
- W2066895159 countsByYear W20668951592013 @default.
- W2066895159 countsByYear W20668951592014 @default.
- W2066895159 countsByYear W20668951592015 @default.
- W2066895159 countsByYear W20668951592016 @default.
- W2066895159 countsByYear W20668951592017 @default.
- W2066895159 countsByYear W20668951592018 @default.
- W2066895159 countsByYear W20668951592019 @default.
- W2066895159 countsByYear W20668951592020 @default.
- W2066895159 countsByYear W20668951592021 @default.
- W2066895159 countsByYear W20668951592023 @default.
- W2066895159 crossrefType "journal-article" @default.
- W2066895159 hasAuthorship W2066895159A5007105396 @default.
- W2066895159 hasAuthorship W2066895159A5020597164 @default.
- W2066895159 hasAuthorship W2066895159A5028774110 @default.
- W2066895159 hasAuthorship W2066895159A5032415345 @default.
- W2066895159 hasAuthorship W2066895159A5066808555 @default.
- W2066895159 hasAuthorship W2066895159A5067443541 @default.
- W2066895159 hasAuthorship W2066895159A5084687544 @default.
- W2066895159 hasConcept C10390740 @default.
- W2066895159 hasConcept C112705442 @default.
- W2066895159 hasConcept C179998833 @default.
- W2066895159 hasConcept C185592680 @default.
- W2066895159 hasConcept C2777379063 @default.
- W2066895159 hasConcept C43617362 @default.
- W2066895159 hasConcept C71924100 @default.
- W2066895159 hasConcept C98274493 @default.
- W2066895159 hasConceptScore W2066895159C10390740 @default.
- W2066895159 hasConceptScore W2066895159C112705442 @default.
- W2066895159 hasConceptScore W2066895159C179998833 @default.
- W2066895159 hasConceptScore W2066895159C185592680 @default.
- W2066895159 hasConceptScore W2066895159C2777379063 @default.
- W2066895159 hasConceptScore W2066895159C43617362 @default.
- W2066895159 hasConceptScore W2066895159C71924100 @default.
- W2066895159 hasConceptScore W2066895159C98274493 @default.
- W2066895159 hasIssue "11" @default.
- W2066895159 hasLocation W20668951591 @default.
- W2066895159 hasLocation W20668951592 @default.
- W2066895159 hasOpenAccess W2066895159 @default.
- W2066895159 hasPrimaryLocation W20668951591 @default.
- W2066895159 hasRelatedWork W1973892552 @default.
- W2066895159 hasRelatedWork W1986005472 @default.
- W2066895159 hasRelatedWork W2039012166 @default.
- W2066895159 hasRelatedWork W2077423873 @default.
- W2066895159 hasRelatedWork W2090751845 @default.
- W2066895159 hasRelatedWork W2093917715 @default.
- W2066895159 hasRelatedWork W2161957616 @default.
- W2066895159 hasRelatedWork W2474278154 @default.
- W2066895159 hasRelatedWork W2601524031 @default.
- W2066895159 hasRelatedWork W3200692342 @default.
- W2066895159 hasVolume "15" @default.
- W2066895159 isParatext "false" @default.
- W2066895159 isRetracted "false" @default.
- W2066895159 magId "2066895159" @default.
- W2066895159 workType "article" @default.