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- W2066925087 abstract "A 59-year-old female was admitted to our hospital because of massive ascites and increasing jaundice, suggesting a severe decompensated state of liver cirrhosis. On the third hospital day, she was diagnosed as disseminated intravascular coagulation (DIC) from a coagulofibrinolytic study and developed renal failure. Continuous drip infusion of gabexate mesilate, a synthetic inhibitor of serine-protease, was found to be successful in managing DIC, followed by the restoration of renal function. During the clinical course, blood endotoxin, assayed by the chromogenic method, was initially 11 pg/ml and increased, in accordance with the elevation of serum FDP, to a level of 110 pg/ml when renal failure occurred. A proportional relationship was observed between changes in blood endotoxin and serum FDP throughout the course. This finding may be an important clue in studying the mechanism of DIC and non-septic endotoxemia both developing in liver cirrhosis." @default.
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- W2066925087 date "1987-01-01" @default.
- W2066925087 modified "2023-10-03" @default.
- W2066925087 title "A case of liver cirrhosis complicated with endotoxemia and disseminated intravascular coagulation : A case report." @default.
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- W2066925087 doi "https://doi.org/10.1620/tjem.151.269" @default.
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