FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066984902> ?p ?o ?g. }

• W2066984902 endingPage "374" @default.
• W2066984902 startingPage "364" @default.
• W2066984902 abstract "Cigarette smoking and the common B1 allele of the TaqIB polymorphism have both been reported to be associated with increased cholesteryl ester transfer protein (CETP) activity and altered lipoprotein levels. Thus, it is possible that the combined presence of these two respective environmental and genetic factors may enhance cardiovascular risk. We hypothesized that susceptibility to early onset myocardial infarction (MI) among cigarette smokers may be related to the presence of TaqIB polymorphism in the CETP gene.The age at onset of a first MI among current (n = 199), past (n = 345), and never (n = 270) smokers was related to the presence of the TaqIB1 and B2 alleles in a cohort of 814 first MI patients.Multivariate regression analysis demonstrated that cigarette smoking was associated with a significant increase in the risk for early onset MI only among carriers of the TaqIB1 allele: current smokers with the B1B1 and B1B2 genotypes displayed a respective 9.4 (P < 0.001) and 8.4 (P < 0.001) year reduction in the age at onset of a first MI compared with never smokers, and past smokers with these genotypes exhibited a respective 3.8 (P = 0.003) and 3.7 (P = 0.01) year reduction. By contrast, current and past smoking was not associated with a significant increase in the risk for early onset MI among B2B2 homozygotes (3.0 [P = 0.28] and 0.2 [P = 0.93] year reduction, respectively). The smoking x genotype interaction was statistically significant (P = 0.04).The current findings suggest that genetic factors may modify susceptibility to early onset MI among cigarette smokers." @default.
• W2066984902 created "2016-06-24" @default.
• W2066984902 creator A5002121570 @default.
• W2066984902 creator A5012733429 @default.
• W2066984902 creator A5018394344 @default.
• W2066984902 creator A5026826956 @default.
• W2066984902 creator A5050596057 @default.
• W2066984902 creator A5059052503 @default.
• W2066984902 creator A5076422519 @default.
• W2066984902 creator A5077082770 @default.
• W2066984902 date "2007-10-01" @default.
• W2066984902 modified "2023-10-16" @default.
• W2066984902 title "Polymorphism in the Cholesteryl Ester Transfer Protein Gene and the Risk of Early Onset Myocardial Infarction among Cigarette Smokers" @default.
• W2066984902 cites W1757354807 @default.
• W2066984902 cites W1930168886 @default.
• W2066984902 cites W1972558162 @default.
• W2066984902 cites W1974435920 @default.
• W2066984902 cites W1982225809 @default.
• W2066984902 cites W2003663774 @default.
• W2066984902 cites W2005247682 @default.
• W2066984902 cites W2008587311 @default.
• W2066984902 cites W2017480132 @default.
• W2066984902 cites W2026389035 @default.
• W2066984902 cites W2035327148 @default.
• W2066984902 cites W2062832606 @default.
• W2066984902 cites W2065423518 @default.
• W2066984902 cites W2077760013 @default.
• W2066984902 cites W2079443737 @default.
• W2066984902 cites W2091867080 @default.
• W2066984902 cites W2094647069 @default.
• W2066984902 cites W2098058160 @default.
• W2066984902 cites W2103677927 @default.
• W2066984902 cites W2116404316 @default.
• W2066984902 cites W2123337267 @default.
• W2066984902 cites W2133359394 @default.
• W2066984902 cites W2148609678 @default.
• W2066984902 cites W2148635162 @default.
• W2066984902 cites W2155588817 @default.
• W2066984902 cites W2166496034 @default.
• W2066984902 cites W2347117299 @default.
• W2066984902 cites W2569586089 @default.
• W2066984902 cites W4248915497 @default.
• W2066984902 doi "https://doi.org/10.1111/j.1542-474x.2007.00186.x" @default.
• W2066984902 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6932528" @default.
• W2066984902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17970962" @default.
• W2066984902 hasPublicationYear "2007" @default.
• W2066984902 type Work @default.
• W2066984902 sameAs 2066984902 @default.
• W2066984902 citedByCount "12" @default.
• W2066984902 countsByYear W20669849022013 @default.
• W2066984902 countsByYear W20669849022014 @default.
• W2066984902 countsByYear W20669849022016 @default.
• W2066984902 countsByYear W20669849022019 @default.
• W2066984902 crossrefType "journal-article" @default.
• W2066984902 hasAuthorship W2066984902A5002121570 @default.
• W2066984902 hasAuthorship W2066984902A5012733429 @default.
• W2066984902 hasAuthorship W2066984902A5018394344 @default.
• W2066984902 hasAuthorship W2066984902A5026826956 @default.
• W2066984902 hasAuthorship W2066984902A5050596057 @default.
• W2066984902 hasAuthorship W2066984902A5059052503 @default.
• W2066984902 hasAuthorship W2066984902A5076422519 @default.
• W2066984902 hasAuthorship W2066984902A5077082770 @default.
• W2066984902 hasBestOaLocation W20669849022 @default.
• W2066984902 hasConcept C104317684 @default.
• W2066984902 hasConcept C126322002 @default.
• W2066984902 hasConcept C134018914 @default.
• W2066984902 hasConcept C135763542 @default.
• W2066984902 hasConcept C164705383 @default.
• W2066984902 hasConcept C180754005 @default.
• W2066984902 hasConcept C2778163477 @default.
• W2066984902 hasConcept C2780072125 @default.
• W2066984902 hasConcept C45505151 @default.
• W2066984902 hasConcept C500558357 @default.
• W2066984902 hasConcept C54355233 @default.
• W2066984902 hasConcept C71924100 @default.
• W2066984902 hasConcept C72563966 @default.
• W2066984902 hasConcept C86803240 @default.
• W2066984902 hasConcept C90924648 @default.
• W2066984902 hasConceptScore W2066984902C104317684 @default.
• W2066984902 hasConceptScore W2066984902C126322002 @default.
• W2066984902 hasConceptScore W2066984902C134018914 @default.
• W2066984902 hasConceptScore W2066984902C135763542 @default.
• W2066984902 hasConceptScore W2066984902C164705383 @default.
• W2066984902 hasConceptScore W2066984902C180754005 @default.
• W2066984902 hasConceptScore W2066984902C2778163477 @default.
• W2066984902 hasConceptScore W2066984902C2780072125 @default.
• W2066984902 hasConceptScore W2066984902C45505151 @default.
• W2066984902 hasConceptScore W2066984902C500558357 @default.
• W2066984902 hasConceptScore W2066984902C54355233 @default.
• W2066984902 hasConceptScore W2066984902C71924100 @default.
• W2066984902 hasConceptScore W2066984902C72563966 @default.
• W2066984902 hasConceptScore W2066984902C86803240 @default.
• W2066984902 hasConceptScore W2066984902C90924648 @default.
• W2066984902 hasIssue "4" @default.
• W2066984902 hasLocation W20669849021 @default.
• W2066984902 hasLocation W20669849022 @default.
• W2066984902 hasLocation W20669849023 @default.
• W2066984902 hasLocation W20669849024 @default.

• next