FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067016673> ?p ?o ?g. }

• W2067016673 endingPage "725" @default.
• W2067016673 startingPage "711" @default.
• W2067016673 abstract "Laminins (Ln), together with Type IV collagen and nidogen-1, form the structural integrity of the basement membranes (BM). In this study we used immunohistochemistry to show the distribution of laminin chains alpha1, alpha3, alpha5, beta1, beta2, beta3, gamma1, gamma2, as well as Type IV collagen, in various types of carcinomas and in normal tissues. Except for diffuse gastric carcinomas and infiltrative breast carcinomas, the malignant epithelial tumor clusters were surrounded by quite a continuous BM in most tumors. These BMs comprised most abundantly Ln alpha5, beta1, and gamma1 chains. Conversely, the Ln alpha1 chain, a component of laminins-1 and -3, showed the most restricted distribution in BMs of both normal tissues and malignancies, being moderately present in carcinomas of thyroid gland and ovary and in intraductal carcinomas of breast. In other types of carcinomas, immunoreactivity for Ln alpha1 chain was found more randomly and was practically negative in carcinomas of tongue, stomach, and colon. These findings were comparable to those observed by in situ hybridization, which showed that carcinomas of thyroid gland and intraductal carcinomas of breast constitutively expressed Ln alpha1 mRNA and that the epithelial tumor cells were the main producers of it. The results suggest that epithelial malignancies, except for infiltrative breast and diffuse gastric carcinomas, produce more notable amounts of BM macromolecules in their growth substratum than has previously been anticipated. Corroborating their widespread distribution in normal epithelial tissues, the chains of Lns-5 and -10 are the most abundant Ln molecules in the corresponding carcinomas." @default.
• W2067016673 created "2016-06-24" @default.
• W2067016673 creator A5022218689 @default.
• W2067016673 creator A5040634343 @default.
• W2067016673 creator A5046060163 @default.
• W2067016673 creator A5061024067 @default.
• W2067016673 date "2001-06-01" @default.
• W2067016673 modified "2023-10-17" @default.
• W2067016673 title "Comparative Analysis of the Distribution of Laminin Chains in the Basement Membranes in Some Malignant Epithelial Tumors: The α1 Chain of Laminin Shows a Selected Expression Pattern in Human Carcinomas" @default.
• W2067016673 cites W1484745378 @default.
• W2067016673 cites W1567770297 @default.
• W2067016673 cites W1582065993 @default.
• W2067016673 cites W1603486799 @default.
• W2067016673 cites W1657169072 @default.
• W2067016673 cites W1878446582 @default.
• W2067016673 cites W1971325550 @default.
• W2067016673 cites W1978837916 @default.
• W2067016673 cites W1983509466 @default.
• W2067016673 cites W1986413400 @default.
• W2067016673 cites W1986613552 @default.
• W2067016673 cites W1989145212 @default.
• W2067016673 cites W1992814841 @default.
• W2067016673 cites W2017953526 @default.
• W2067016673 cites W2024818970 @default.
• W2067016673 cites W2025361420 @default.
• W2067016673 cites W2049451860 @default.
• W2067016673 cites W2050069938 @default.
• W2067016673 cites W2052728159 @default.
• W2067016673 cites W2057378658 @default.
• W2067016673 cites W2065584855 @default.
• W2067016673 cites W2072331169 @default.
• W2067016673 cites W2080327002 @default.
• W2067016673 cites W2085566447 @default.
• W2067016673 cites W2089276240 @default.
• W2067016673 cites W2091100304 @default.
• W2067016673 cites W2091212646 @default.
• W2067016673 cites W2093514870 @default.
• W2067016673 cites W2100837269 @default.
• W2067016673 cites W2104692426 @default.
• W2067016673 cites W2105273730 @default.
• W2067016673 cites W2107564206 @default.
• W2067016673 cites W2112770618 @default.
• W2067016673 cites W2114306533 @default.
• W2067016673 cites W2119622097 @default.
• W2067016673 cites W2121513486 @default.
• W2067016673 cites W2123341137 @default.
• W2067016673 cites W2138316626 @default.
• W2067016673 cites W2138919048 @default.
• W2067016673 cites W2143987989 @default.
• W2067016673 cites W2165123145 @default.
• W2067016673 cites W2166703723 @default.
• W2067016673 cites W2167696515 @default.
• W2067016673 cites W2167970431 @default.
• W2067016673 cites W2168058510 @default.
• W2067016673 cites W2200231061 @default.
• W2067016673 doi "https://doi.org/10.1177/002215540104900605" @default.
• W2067016673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11373318" @default.
• W2067016673 hasPublicationYear "2001" @default.
• W2067016673 type Work @default.
• W2067016673 sameAs 2067016673 @default.
• W2067016673 citedByCount "75" @default.
• W2067016673 countsByYear W20670166732012 @default.
• W2067016673 countsByYear W20670166732013 @default.
• W2067016673 countsByYear W20670166732014 @default.
• W2067016673 countsByYear W20670166732016 @default.
• W2067016673 countsByYear W20670166732017 @default.
• W2067016673 countsByYear W20670166732018 @default.
• W2067016673 countsByYear W20670166732020 @default.
• W2067016673 countsByYear W20670166732021 @default.
• W2067016673 countsByYear W20670166732022 @default.
• W2067016673 crossrefType "journal-article" @default.
• W2067016673 hasAuthorship W2067016673A5022218689 @default.
• W2067016673 hasAuthorship W2067016673A5040634343 @default.
• W2067016673 hasAuthorship W2067016673A5046060163 @default.
• W2067016673 hasAuthorship W2067016673A5061024067 @default.
• W2067016673 hasBestOaLocation W20670166731 @default.
• W2067016673 hasConcept C134018914 @default.
• W2067016673 hasConcept C142724271 @default.
• W2067016673 hasConcept C185592680 @default.
• W2067016673 hasConcept C189165786 @default.
• W2067016673 hasConcept C204232928 @default.
• W2067016673 hasConcept C2776193487 @default.
• W2067016673 hasConcept C2777107211 @default.
• W2067016673 hasConcept C2777546739 @default.
• W2067016673 hasConcept C2779814568 @default.
• W2067016673 hasConcept C526584372 @default.
• W2067016673 hasConcept C529295009 @default.
• W2067016673 hasConcept C71924100 @default.
• W2067016673 hasConcept C86803240 @default.
• W2067016673 hasConcept C95444343 @default.
• W2067016673 hasConceptScore W2067016673C134018914 @default.
• W2067016673 hasConceptScore W2067016673C142724271 @default.
• W2067016673 hasConceptScore W2067016673C185592680 @default.
• W2067016673 hasConceptScore W2067016673C189165786 @default.
• W2067016673 hasConceptScore W2067016673C204232928 @default.
• W2067016673 hasConceptScore W2067016673C2776193487 @default.
• W2067016673 hasConceptScore W2067016673C2777107211 @default.
• W2067016673 hasConceptScore W2067016673C2777546739 @default.

• next