Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067066970> ?p ?o ?g. }
- W2067066970 endingPage "15919" @default.
- W2067066970 startingPage "15919" @default.
- W2067066970 abstract "Our studies focus on controlled and tuned biodegradation, mechanism of biodegradation, biocompatibility, genotoxicity and controlled and sustained drug release performance of poly(hydroxybutyrate-co-valerate) nanohybrids. Nanohybrids were prepared using layered silicates with two different surface modifiers through a solution route. Biodegradation has been investigated in compost, microorganisms (pseudomonas stutzeri) and pure enzymes, showing both enhanced and suppressed rates as compared to that of the pure polymer. Two nanoclays that increased the strong filler dependency phenomena were used to control the biodegradation rate. Complete biodegradation mechanism has been revealed, which indicates that the pH of the medium dictates the rate of biodegradation by activating the enzyme responsible for degradation. Biodegradation has also been controlled by optimizing the processing conditions of the specimens. Biocompatibility of the nanohybrids has been tested at the intra-cellular level by sub-cellular localization of HIPK2 protein, in addition to the typical cell adherence on the nanohybrid films demonstrating that there is no induced genotoxic stress either from the polymer or from the nanoparticles. Biocompatible nanohybrids have been used for drug delivery, showing sustained and controlled release of drugs in presence of nanoparticles. Hence, the developed nanohybrids illustrate potential biomaterials for tissue engineering and drug delivery." @default.
- W2067066970 created "2016-06-24" @default.
- W2067066970 creator A5001048896 @default.
- W2067066970 creator A5005379720 @default.
- W2067066970 creator A5019859845 @default.
- W2067066970 creator A5024511684 @default.
- W2067066970 creator A5038875502 @default.
- W2067066970 creator A5040166548 @default.
- W2067066970 creator A5049150802 @default.
- W2067066970 date "2011-01-01" @default.
- W2067066970 modified "2023-10-16" @default.
- W2067066970 title "Tuned biodegradation using poly(hydroxybutyrate-co-valerate) nanobiohybrids: Emerging biomaterials for tissue engineering and drug delivery" @default.
- W2067066970 cites W1514068331 @default.
- W2067066970 cites W1964086098 @default.
- W2067066970 cites W1971419066 @default.
- W2067066970 cites W1975965166 @default.
- W2067066970 cites W1982313772 @default.
- W2067066970 cites W1983794369 @default.
- W2067066970 cites W1988386903 @default.
- W2067066970 cites W1993105877 @default.
- W2067066970 cites W2004748614 @default.
- W2067066970 cites W2014785305 @default.
- W2067066970 cites W2014929029 @default.
- W2067066970 cites W2023083550 @default.
- W2067066970 cites W2026457034 @default.
- W2067066970 cites W2034809261 @default.
- W2067066970 cites W2039517105 @default.
- W2067066970 cites W2042626809 @default.
- W2067066970 cites W2051474403 @default.
- W2067066970 cites W2052660229 @default.
- W2067066970 cites W2054059240 @default.
- W2067066970 cites W2055096547 @default.
- W2067066970 cites W2057455489 @default.
- W2067066970 cites W2057642744 @default.
- W2067066970 cites W2058095142 @default.
- W2067066970 cites W2062978844 @default.
- W2067066970 cites W2065762680 @default.
- W2067066970 cites W2066865030 @default.
- W2067066970 cites W2067668561 @default.
- W2067066970 cites W2076169545 @default.
- W2067066970 cites W2078497186 @default.
- W2067066970 cites W2078751866 @default.
- W2067066970 cites W2086463203 @default.
- W2067066970 cites W2124209721 @default.
- W2067066970 cites W2138919043 @default.
- W2067066970 cites W2167680304 @default.
- W2067066970 cites W2326319875 @default.
- W2067066970 cites W3016895068 @default.
- W2067066970 doi "https://doi.org/10.1039/c1jm12427g" @default.
- W2067066970 hasPublicationYear "2011" @default.
- W2067066970 type Work @default.
- W2067066970 sameAs 2067066970 @default.
- W2067066970 citedByCount "29" @default.
- W2067066970 countsByYear W20670669702012 @default.
- W2067066970 countsByYear W20670669702013 @default.
- W2067066970 countsByYear W20670669702014 @default.
- W2067066970 countsByYear W20670669702015 @default.
- W2067066970 countsByYear W20670669702016 @default.
- W2067066970 countsByYear W20670669702017 @default.
- W2067066970 countsByYear W20670669702018 @default.
- W2067066970 countsByYear W20670669702019 @default.
- W2067066970 countsByYear W20670669702020 @default.
- W2067066970 countsByYear W20670669702021 @default.
- W2067066970 countsByYear W20670669702022 @default.
- W2067066970 crossrefType "journal-article" @default.
- W2067066970 hasAuthorship W2067066970A5001048896 @default.
- W2067066970 hasAuthorship W2067066970A5005379720 @default.
- W2067066970 hasAuthorship W2067066970A5019859845 @default.
- W2067066970 hasAuthorship W2067066970A5024511684 @default.
- W2067066970 hasAuthorship W2067066970A5038875502 @default.
- W2067066970 hasAuthorship W2067066970A5040166548 @default.
- W2067066970 hasAuthorship W2067066970A5049150802 @default.
- W2067066970 hasConcept C100544194 @default.
- W2067066970 hasConcept C127413603 @default.
- W2067066970 hasConcept C136229726 @default.
- W2067066970 hasConcept C155672457 @default.
- W2067066970 hasConcept C157021035 @default.
- W2067066970 hasConcept C171250308 @default.
- W2067066970 hasConcept C178790620 @default.
- W2067066970 hasConcept C185592680 @default.
- W2067066970 hasConcept C192562407 @default.
- W2067066970 hasConcept C2776753739 @default.
- W2067066970 hasConcept C2776979534 @default.
- W2067066970 hasConcept C2777230088 @default.
- W2067066970 hasConcept C2779820397 @default.
- W2067066970 hasConcept C42360764 @default.
- W2067066970 hasConcept C49892992 @default.
- W2067066970 hasConcept C521977710 @default.
- W2067066970 hasConcept C71924100 @default.
- W2067066970 hasConceptScore W2067066970C100544194 @default.
- W2067066970 hasConceptScore W2067066970C127413603 @default.
- W2067066970 hasConceptScore W2067066970C136229726 @default.
- W2067066970 hasConceptScore W2067066970C155672457 @default.
- W2067066970 hasConceptScore W2067066970C157021035 @default.
- W2067066970 hasConceptScore W2067066970C171250308 @default.
- W2067066970 hasConceptScore W2067066970C178790620 @default.
- W2067066970 hasConceptScore W2067066970C185592680 @default.
- W2067066970 hasConceptScore W2067066970C192562407 @default.