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• W2067116007 startingPage "138" @default.
• W2067116007 abstract "The saliva of the mosquito Aedes aegypti has previously been reported to contain a 1400-Da peptide with pharmacological properties typical of a tachykinin. In the present study this vasodilator has been purified to homogeneity and found to consist of two peptides: sialokinin I, with the sequence Asn-Thr-Gly-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2, and sialokinin II, identical to sialokinin I except for an Asp in position 1. These peptides are present in amounts of 0.62 and 0.16 pmol (711 and 178 ng), respectively, per salivary gland pair. When assayed on the guinea pig ileum, both peptides are as active as the mammalian tachykinin substance P, with K0.5 values of 5.07, 6.58, and 4.94 nM for sialokinin I, sialokinin II, and substance P, respectively." @default.
• W2067116007 created "2016-06-24" @default.
• W2067116007 creator A5007924348 @default.
• W2067116007 creator A5037580313 @default.
• W2067116007 date "1994-01-04" @default.
• W2067116007 modified "2023-10-18" @default.
• W2067116007 title "Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti." @default.
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• W2067116007 doi "https://doi.org/10.1073/pnas.91.1.138" @default.
• W2067116007 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/42901" @default.
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