Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067141805> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2067141805 endingPage "257" @default.
- W2067141805 startingPage "253" @default.
- W2067141805 abstract "To develop an in vitro experimental model of vascular smooth muscle cell hyperplasia, a major feature in chronic cardiac rejection, we studied a novel vascular smooth muscle cell line, P53LMAC01 (AC01), which was established from aortic smooth muscles of p53 knock-out mice, to determine its response to a platelet-derived growth factor (PDGF) and to Cyclosporin A (CsA). The responses were compared with those of human aortic smooth muscle cells (AOSMC). The AC01 exhibited a distinct proliferative response to PDGF similar to that of AOSMC under serum-free conditions. 10 ng/ml of PDGF–BB increased by a factor of 4.5 and PDGF–AB doubled the thymidine uptake, but PDGF–AA caused only a slight increase. The proliferation was markedly inhibited by 10−6 M of CsA but less affected by 10−7 M. These results indicate that the AC01 cell line could provide a convenient experimental system for investigating chronic rejection in vitro and that the system might work as a screening model of agents for treating transplant-related arteriosclerosis." @default.
- W2067141805 created "2016-06-24" @default.
- W2067141805 creator A5045394110 @default.
- W2067141805 creator A5048833058 @default.
- W2067141805 creator A5065381442 @default.
- W2067141805 creator A5077281495 @default.
- W2067141805 date "2001-02-01" @default.
- W2067141805 modified "2023-09-24" @default.
- W2067141805 title "The proliferative response of p53 knock-out mouse-derived vascular smooth muscle cell line, P53LMAC01, to PDGF, when compared with human aortic smooth muscle cells" @default.
- W2067141805 cites W106423502 @default.
- W2067141805 cites W1969552991 @default.
- W2067141805 cites W1993272620 @default.
- W2067141805 cites W1997184941 @default.
- W2067141805 cites W2006199359 @default.
- W2067141805 cites W2017153705 @default.
- W2067141805 cites W2088451454 @default.
- W2067141805 cites W2148371225 @default.
- W2067141805 cites W2155321232 @default.
- W2067141805 cites W2399732437 @default.
- W2067141805 doi "https://doi.org/10.1016/s0966-3274(01)00029-6" @default.
- W2067141805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11316068" @default.
- W2067141805 hasPublicationYear "2001" @default.
- W2067141805 type Work @default.
- W2067141805 sameAs 2067141805 @default.
- W2067141805 citedByCount "3" @default.
- W2067141805 countsByYear W20671418052020 @default.
- W2067141805 crossrefType "journal-article" @default.
- W2067141805 hasAuthorship W2067141805A5045394110 @default.
- W2067141805 hasAuthorship W2067141805A5048833058 @default.
- W2067141805 hasAuthorship W2067141805A5065381442 @default.
- W2067141805 hasAuthorship W2067141805A5077281495 @default.
- W2067141805 hasConcept C126322002 @default.
- W2067141805 hasConcept C134018914 @default.
- W2067141805 hasConcept C1491633281 @default.
- W2067141805 hasConcept C170493617 @default.
- W2067141805 hasConcept C180361614 @default.
- W2067141805 hasConcept C202751555 @default.
- W2067141805 hasConcept C207200792 @default.
- W2067141805 hasConcept C2775960820 @default.
- W2067141805 hasConcept C2777562237 @default.
- W2067141805 hasConcept C2779395532 @default.
- W2067141805 hasConcept C2781294074 @default.
- W2067141805 hasConcept C2992686903 @default.
- W2067141805 hasConcept C502942594 @default.
- W2067141805 hasConcept C54355233 @default.
- W2067141805 hasConcept C55493867 @default.
- W2067141805 hasConcept C62112901 @default.
- W2067141805 hasConcept C71924100 @default.
- W2067141805 hasConcept C81885089 @default.
- W2067141805 hasConcept C86803240 @default.
- W2067141805 hasConcept C95444343 @default.
- W2067141805 hasConceptScore W2067141805C126322002 @default.
- W2067141805 hasConceptScore W2067141805C134018914 @default.
- W2067141805 hasConceptScore W2067141805C1491633281 @default.
- W2067141805 hasConceptScore W2067141805C170493617 @default.
- W2067141805 hasConceptScore W2067141805C180361614 @default.
- W2067141805 hasConceptScore W2067141805C202751555 @default.
- W2067141805 hasConceptScore W2067141805C207200792 @default.
- W2067141805 hasConceptScore W2067141805C2775960820 @default.
- W2067141805 hasConceptScore W2067141805C2777562237 @default.
- W2067141805 hasConceptScore W2067141805C2779395532 @default.
- W2067141805 hasConceptScore W2067141805C2781294074 @default.
- W2067141805 hasConceptScore W2067141805C2992686903 @default.
- W2067141805 hasConceptScore W2067141805C502942594 @default.
- W2067141805 hasConceptScore W2067141805C54355233 @default.
- W2067141805 hasConceptScore W2067141805C55493867 @default.
- W2067141805 hasConceptScore W2067141805C62112901 @default.
- W2067141805 hasConceptScore W2067141805C71924100 @default.
- W2067141805 hasConceptScore W2067141805C81885089 @default.
- W2067141805 hasConceptScore W2067141805C86803240 @default.
- W2067141805 hasConceptScore W2067141805C95444343 @default.
- W2067141805 hasIssue "4" @default.
- W2067141805 hasLocation W20671418051 @default.
- W2067141805 hasLocation W20671418052 @default.
- W2067141805 hasOpenAccess W2067141805 @default.
- W2067141805 hasPrimaryLocation W20671418051 @default.
- W2067141805 hasRelatedWork W1992731515 @default.
- W2067141805 hasRelatedWork W2001668238 @default.
- W2067141805 hasRelatedWork W2055810659 @default.
- W2067141805 hasRelatedWork W2086086028 @default.
- W2067141805 hasRelatedWork W2369516964 @default.
- W2067141805 hasRelatedWork W2371437420 @default.
- W2067141805 hasRelatedWork W2765685634 @default.
- W2067141805 hasRelatedWork W3154189534 @default.
- W2067141805 hasRelatedWork W339979645 @default.
- W2067141805 hasRelatedWork W4230024640 @default.
- W2067141805 hasVolume "8" @default.
- W2067141805 isParatext "false" @default.
- W2067141805 isRetracted "false" @default.
- W2067141805 magId "2067141805" @default.
- W2067141805 workType "article" @default.