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• W2067154781 abstract "Objective: To present a case of multiple endocrine neoplasia type 2B (MEN2B) with a prolonged course. Methods: We describe the clinical, laboratory, and radiologic findings in a patient with MEN2B and review the various interventions during a period of approximately 3 decades. Results: In 1962, a 19-year-old man with a marfanoid body habitus presented with multiple thyroid nodules and neurofibromas of the tongue. Total thyroidectomy demonstrated multicentric medullary thyroid carcinoma with cervical lymph node metastatic involvement. At the time of the first description of the MEN2B syndrome, the patient was enrolled in a surveillance program. An increase in urinary metanephrines resulted in bilateral adrenalectomy for multinodular pheochromocytoma in 1972. Increased serum calcitonin levels and the appearance of cervical lymphadenopathy led to modified radical neck dissection 12 years after the initial diagnosis of medullary thyroid carcinoma. In 1975, angiography revealed extensive hepatic lesions metast..." @default.
• W2067154781 created "2016-06-24" @default.
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• W2067154781 date "2003-01-01" @default.
• W2067154781 modified "2023-10-17" @default.
• W2067154781 title "Prolonged Survival of a Patient with Multiple Endocrine Neoplasia Type 2b and Stage IV Medullary Thyroid Carcinoma" @default.
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• W2067154781 doi "https://doi.org/10.4158/ep.9.1.45" @default.
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