FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067173627> ?p ?o ?g. }

• W2067173627 endingPage "645" @default.
• W2067173627 startingPage "631" @default.
• W2067173627 abstract "The molecular basis of the immunotoxic effect of ammonium metavanadate on signal transduction involved in macrophage activation was studied in resident peritoneal macrophages PEM and a murine macrophage like cell line J774 A fourfold elevation in cytosolic free calcium levels was observed within 10 s following lipopolysaccharide LPS stimulation of the non vanadate exposed controls both in vitro and in vivo the levels returned to prestimulation values within 70 s Exposure to phorbol ester PMA did not result in any appreciable change in cytosolic free calcium levels Compared to untreated controls treatment with vanadate caused a significant elevation in basal cytosolic calcium levels Such elevation was not enhanced further by LPS LPS stimulation of macrophages also resulted in a significant elevation of membrane associated protein kinase C PKC activity which was however inhibited in a dose dependent manner by vanadate in both in vitro and in vivo studies Exposure to PMA also resulted in a significant elevation of membrane associated PKC activity vanadate treatment at lower levels did not cause downregulation indicating that vanadate at these levels interfered with the receptor medi ated events rather than the enzyme directly Vanadate at higher exposure levels inhibited the activity even in PMA stimulated macrophages No significant difference occurred in cytosolic PKC activities in control macrophages vanadate treatment at lower levels resulted in a significant elevation of cytosolic PKC activities following stimulation with LPS or PMA indicating that vanadate might be interfering with the translocation process" @default.
• W2067173627 created "2016-06-24" @default.
• W2067173627 creator A5078443880 @default.
• W2067173627 creator A5080215137 @default.
• W2067173627 date "1996-12-01" @default.
• W2067173627 modified "2023-09-27" @default.
• W2067173627 title "MODULATION OF MACROPHAGE ACTIVATION BY AMMONIUM METAVANADATE" @default.
• W2067173627 cites W1494669487 @default.
• W2067173627 cites W151864754 @default.
• W2067173627 cites W1530574567 @default.
• W2067173627 cites W1587745196 @default.
• W2067173627 cites W1964839077 @default.
• W2067173627 cites W1983043868 @default.
• W2067173627 cites W2004930733 @default.
• W2067173627 cites W2009674713 @default.
• W2067173627 cites W2009856702 @default.
• W2067173627 cites W2012804866 @default.
• W2067173627 cites W2021765529 @default.
• W2067173627 cites W2030971353 @default.
• W2067173627 cites W2035272662 @default.
• W2067173627 cites W2039568214 @default.
• W2067173627 cites W2042421589 @default.
• W2067173627 cites W2044469415 @default.
• W2067173627 cites W2045870780 @default.
• W2067173627 cites W2047168873 @default.
• W2067173627 cites W2050890071 @default.
• W2067173627 cites W2056853110 @default.
• W2067173627 cites W2081031657 @default.
• W2067173627 cites W2092002488 @default.
• W2067173627 cites W2094298299 @default.
• W2067173627 cites W2122999278 @default.
• W2067173627 cites W2152625320 @default.
• W2067173627 cites W2345816375 @default.
• W2067173627 cites W2115313543 @default.
• W2067173627 doi "https://doi.org/10.1080/009841096160673" @default.
• W2067173627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8977629" @default.
• W2067173627 hasPublicationYear "1996" @default.
• W2067173627 type Work @default.
• W2067173627 sameAs 2067173627 @default.
• W2067173627 citedByCount "5" @default.
• W2067173627 countsByYear W20671736272018 @default.
• W2067173627 countsByYear W20671736272022 @default.
• W2067173627 crossrefType "journal-article" @default.
• W2067173627 hasAuthorship W2067173627A5078443880 @default.
• W2067173627 hasAuthorship W2067173627A5080215137 @default.
• W2067173627 hasConcept C126322002 @default.
• W2067173627 hasConcept C134018914 @default.
• W2067173627 hasConcept C150903083 @default.
• W2067173627 hasConcept C161790260 @default.
• W2067173627 hasConcept C181199279 @default.
• W2067173627 hasConcept C185592680 @default.
• W2067173627 hasConcept C195794163 @default.
• W2067173627 hasConcept C207001950 @default.
• W2067173627 hasConcept C24998067 @default.
• W2067173627 hasConcept C2776641422 @default.
• W2067173627 hasConcept C2780043322 @default.
• W2067173627 hasConcept C2781116636 @default.
• W2067173627 hasConcept C519063684 @default.
• W2067173627 hasConcept C55493867 @default.
• W2067173627 hasConcept C62478195 @default.
• W2067173627 hasConcept C71924100 @default.
• W2067173627 hasConcept C86803240 @default.
• W2067173627 hasConcept C98539663 @default.
• W2067173627 hasConceptScore W2067173627C126322002 @default.
• W2067173627 hasConceptScore W2067173627C134018914 @default.
• W2067173627 hasConceptScore W2067173627C150903083 @default.
• W2067173627 hasConceptScore W2067173627C161790260 @default.
• W2067173627 hasConceptScore W2067173627C181199279 @default.
• W2067173627 hasConceptScore W2067173627C185592680 @default.
• W2067173627 hasConceptScore W2067173627C195794163 @default.
• W2067173627 hasConceptScore W2067173627C207001950 @default.
• W2067173627 hasConceptScore W2067173627C24998067 @default.
• W2067173627 hasConceptScore W2067173627C2776641422 @default.
• W2067173627 hasConceptScore W2067173627C2780043322 @default.
• W2067173627 hasConceptScore W2067173627C2781116636 @default.
• W2067173627 hasConceptScore W2067173627C519063684 @default.
• W2067173627 hasConceptScore W2067173627C55493867 @default.
• W2067173627 hasConceptScore W2067173627C62478195 @default.
• W2067173627 hasConceptScore W2067173627C71924100 @default.
• W2067173627 hasConceptScore W2067173627C86803240 @default.
• W2067173627 hasConceptScore W2067173627C98539663 @default.
• W2067173627 hasIssue "6" @default.
• W2067173627 hasLocation W20671736271 @default.
• W2067173627 hasLocation W20671736272 @default.
• W2067173627 hasOpenAccess W2067173627 @default.
• W2067173627 hasPrimaryLocation W20671736271 @default.
• W2067173627 hasRelatedWork W1956062754 @default.
• W2067173627 hasRelatedWork W2011584433 @default.
• W2067173627 hasRelatedWork W2025162880 @default.
• W2067173627 hasRelatedWork W2040646620 @default.
• W2067173627 hasRelatedWork W2065224155 @default.
• W2067173627 hasRelatedWork W2067173627 @default.
• W2067173627 hasRelatedWork W2102581783 @default.
• W2067173627 hasRelatedWork W2131413156 @default.
• W2067173627 hasRelatedWork W2212096471 @default.
• W2067173627 hasRelatedWork W2351943678 @default.
• W2067173627 hasVolume "49" @default.
• W2067173627 isParatext "false" @default.

• next