Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067187976> ?p ?o ?g. }
- W2067187976 endingPage "13" @default.
- W2067187976 startingPage "1" @default.
- W2067187976 abstract "Cancer related fatigue (CRF) is one of the most common side effects of cancer and its treatments. A large proportion of cancer patients experience cancer-related physical and central fatigue so new strategies are needed for treatment and improved survival of these patients. BST204 was prepared by incubating crude ginseng extract with ginsenoside- β -glucosidase. The purpose of the present study was to examine the effects of BST204, mixture of ginsenosides on 5-fluorouracil (5-FU)-induced CRF, the glycogen synthesis, and biochemical parameters in mice. The mice were randomly divided into the following groups: the naïve normal (normal), the HT-29 cell inoculated (xenograft), xenograft and 5-FU treated (control), xenograft + 5-FU + BST204-treated (100 and 200 mg/kg) (BST204), and xenograft + 5-FU + modafinil (13 mg/kg) treated group (modafinil). Running wheel activity and forced swimming test were used for evaluation of CRF. Muscle glycogen, serum inflammatory cytokines, aspartic aminotransferase (AST), alanine aminotransferase (ALT), creatinine (CRE), white blood cell (WBC), neutrophil (NEUT), red blood cell (RBC), and hemoglobin (HGB) were measured. Treatment with BST204 significantly increased the running wheel activity and forced swimming time compared to the control group. Consistent with the behavioral data, BST204 markedly increased muscle glycogen activity and concentrations of WBC, NEUT, RBC, and HGB. Also, tumor necrosis factor- α (TNF- α ) and interleukin-6 (IL-6), AST, ALT, and CRE levels in the serum were significantly reduced in the BST204-treated group compared to the control group. This result suggests that BST204 may improve chemotherapy-related fatigue and adverse toxic side effects." @default.
- W2067187976 created "2016-06-24" @default.
- W2067187976 creator A5000139012 @default.
- W2067187976 creator A5008985186 @default.
- W2067187976 creator A5046823225 @default.
- W2067187976 creator A5058481084 @default.
- W2067187976 creator A5063520819 @default.
- W2067187976 creator A5070413744 @default.
- W2067187976 date "2015-01-01" @default.
- W2067187976 modified "2023-10-12" @default.
- W2067187976 title "Ginseng Purified Dry Extract, BST204, Improved Cancer Chemotherapy-Related Fatigue and Toxicity in Mice" @default.
- W2067187976 cites W122893665 @default.
- W2067187976 cites W128049518 @default.
- W2067187976 cites W138394970 @default.
- W2067187976 cites W1520162181 @default.
- W2067187976 cites W1536994921 @default.
- W2067187976 cites W1564933160 @default.
- W2067187976 cites W1604761302 @default.
- W2067187976 cites W177185718 @default.
- W2067187976 cites W181263172 @default.
- W2067187976 cites W1858949386 @default.
- W2067187976 cites W1896527885 @default.
- W2067187976 cites W1966370120 @default.
- W2067187976 cites W1966392686 @default.
- W2067187976 cites W1967342027 @default.
- W2067187976 cites W1968869688 @default.
- W2067187976 cites W1971192767 @default.
- W2067187976 cites W1972027018 @default.
- W2067187976 cites W1973563283 @default.
- W2067187976 cites W1973694956 @default.
- W2067187976 cites W1974735562 @default.
- W2067187976 cites W1976224649 @default.
- W2067187976 cites W1976929509 @default.
- W2067187976 cites W1978138839 @default.
- W2067187976 cites W1979563048 @default.
- W2067187976 cites W1981310718 @default.
- W2067187976 cites W1984938280 @default.
- W2067187976 cites W1984988499 @default.
- W2067187976 cites W1987365863 @default.
- W2067187976 cites W1988010258 @default.
- W2067187976 cites W1989418711 @default.
- W2067187976 cites W1989453303 @default.
- W2067187976 cites W1993142992 @default.
- W2067187976 cites W1996428322 @default.
- W2067187976 cites W1996852003 @default.
- W2067187976 cites W1998674850 @default.
- W2067187976 cites W1999867337 @default.
- W2067187976 cites W2000732921 @default.
- W2067187976 cites W2002252503 @default.
- W2067187976 cites W2006302849 @default.
- W2067187976 cites W2007420005 @default.
- W2067187976 cites W2010310943 @default.
- W2067187976 cites W2010319384 @default.
- W2067187976 cites W2017926292 @default.
- W2067187976 cites W2019343318 @default.
- W2067187976 cites W2020543511 @default.
- W2067187976 cites W2024721825 @default.
- W2067187976 cites W2024958133 @default.
- W2067187976 cites W2031958723 @default.
- W2067187976 cites W2033986042 @default.
- W2067187976 cites W2034593408 @default.
- W2067187976 cites W2041080192 @default.
- W2067187976 cites W2041509884 @default.
- W2067187976 cites W2044072446 @default.
- W2067187976 cites W2045819550 @default.
- W2067187976 cites W2046401757 @default.
- W2067187976 cites W2053097516 @default.
- W2067187976 cites W2060889204 @default.
- W2067187976 cites W2061295164 @default.
- W2067187976 cites W2061948405 @default.
- W2067187976 cites W2062470198 @default.
- W2067187976 cites W2064225160 @default.
- W2067187976 cites W2064862494 @default.
- W2067187976 cites W2069275497 @default.
- W2067187976 cites W2074340098 @default.
- W2067187976 cites W2074826639 @default.
- W2067187976 cites W2080722149 @default.
- W2067187976 cites W2081216494 @default.
- W2067187976 cites W2083151439 @default.
- W2067187976 cites W2088751222 @default.
- W2067187976 cites W2089455269 @default.
- W2067187976 cites W2089802936 @default.
- W2067187976 cites W2091105462 @default.
- W2067187976 cites W2101256252 @default.
- W2067187976 cites W2104836169 @default.
- W2067187976 cites W2107251975 @default.
- W2067187976 cites W2111361718 @default.
- W2067187976 cites W2115624769 @default.
- W2067187976 cites W2118549183 @default.
- W2067187976 cites W2120334173 @default.
- W2067187976 cites W2124932143 @default.
- W2067187976 cites W2126795224 @default.
- W2067187976 cites W2128416931 @default.
- W2067187976 cites W2134806201 @default.
- W2067187976 cites W2140364774 @default.
- W2067187976 cites W2143268420 @default.
- W2067187976 cites W2146597482 @default.
- W2067187976 cites W2152415731 @default.