Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067191737> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2067191737 endingPage "400" @default.
- W2067191737 startingPage "395" @default.
- W2067191737 abstract "We previously found that cell surface molecules of approximately 70, approximately 35, approximately 32, approximately 22, and approximately 14 kDa from liver-metastatic murine RAW117 large-cell lymphoma cells bound to target liver microvessel endothelial cells. Isolation and sequencing of the approximately 35-kDa component revealed it to be annexin II, a Ca(2+)-binding molecule involved in cytoskeletal and membrane interactions. Annexin II antibodies inhibited the adhesion of RAW117 tumor cells to live or fixed liver endothelial cells, and purified tumor cell surface fractions containing the approximately 35-kDa component inhibited partially RAW117 cell-endothelial cell adhesion, suggesting a role for annexins in tumor cell-endothelial cell adhesion. In the present study we identified the 70-kDa cell surface component that binds to hepatic sinusoidal endothelial cells in a Ca(2+)-dependent manner as annexin VI. Cytofluorographic analysis indicated that annexin VI was expressed on the cell surface in slightly higher amounts on highly metastatic RAW117 cells, and it was not removable by EDTA treatment. Anti-annexin VI antibodies inhibited the adhesion of RAW117 cells to fixed or unfixed murine hepatic sinusoidal endothelial cells by approximately 40%, indicating a role for annexin VI in mediating a portion of the Ca(2+)-dependent RAW117 cell adhesion to target liver microvessel endothelial cells." @default.
- W2067191737 created "2016-06-24" @default.
- W2067191737 creator A5048164123 @default.
- W2067191737 creator A5053957826 @default.
- W2067191737 creator A5088154120 @default.
- W2067191737 date "1994-12-01" @default.
- W2067191737 modified "2023-09-26" @default.
- W2067191737 title "Extracellular Annexin VI Expression Is Associated with Divalent Cation-Dependent Endothelial Cell Adhesion of Metastatic RAW117 Large-Cell Lymphoma Cells" @default.
- W2067191737 doi "https://doi.org/10.1006/excr.1994.1358" @default.
- W2067191737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7982479" @default.
- W2067191737 hasPublicationYear "1994" @default.
- W2067191737 type Work @default.
- W2067191737 sameAs 2067191737 @default.
- W2067191737 citedByCount "27" @default.
- W2067191737 countsByYear W20671917372012 @default.
- W2067191737 countsByYear W20671917372015 @default.
- W2067191737 countsByYear W20671917372016 @default.
- W2067191737 countsByYear W20671917372017 @default.
- W2067191737 countsByYear W20671917372018 @default.
- W2067191737 countsByYear W20671917372019 @default.
- W2067191737 countsByYear W20671917372022 @default.
- W2067191737 countsByYear W20671917372023 @default.
- W2067191737 crossrefType "journal-article" @default.
- W2067191737 hasAuthorship W2067191737A5048164123 @default.
- W2067191737 hasAuthorship W2067191737A5053957826 @default.
- W2067191737 hasAuthorship W2067191737A5088154120 @default.
- W2067191737 hasConcept C123012128 @default.
- W2067191737 hasConcept C1491633281 @default.
- W2067191737 hasConcept C153911025 @default.
- W2067191737 hasConcept C16224149 @default.
- W2067191737 hasConcept C183521119 @default.
- W2067191737 hasConcept C202751555 @default.
- W2067191737 hasConcept C28406088 @default.
- W2067191737 hasConcept C30345302 @default.
- W2067191737 hasConcept C55493867 @default.
- W2067191737 hasConcept C85789140 @default.
- W2067191737 hasConcept C86803240 @default.
- W2067191737 hasConcept C88634738 @default.
- W2067191737 hasConcept C95444343 @default.
- W2067191737 hasConceptScore W2067191737C123012128 @default.
- W2067191737 hasConceptScore W2067191737C1491633281 @default.
- W2067191737 hasConceptScore W2067191737C153911025 @default.
- W2067191737 hasConceptScore W2067191737C16224149 @default.
- W2067191737 hasConceptScore W2067191737C183521119 @default.
- W2067191737 hasConceptScore W2067191737C202751555 @default.
- W2067191737 hasConceptScore W2067191737C28406088 @default.
- W2067191737 hasConceptScore W2067191737C30345302 @default.
- W2067191737 hasConceptScore W2067191737C55493867 @default.
- W2067191737 hasConceptScore W2067191737C85789140 @default.
- W2067191737 hasConceptScore W2067191737C86803240 @default.
- W2067191737 hasConceptScore W2067191737C88634738 @default.
- W2067191737 hasConceptScore W2067191737C95444343 @default.
- W2067191737 hasIssue "2" @default.
- W2067191737 hasLocation W20671917371 @default.
- W2067191737 hasLocation W20671917372 @default.
- W2067191737 hasOpenAccess W2067191737 @default.
- W2067191737 hasPrimaryLocation W20671917371 @default.
- W2067191737 hasRelatedWork W107255112 @default.
- W2067191737 hasRelatedWork W1790932677 @default.
- W2067191737 hasRelatedWork W1998016140 @default.
- W2067191737 hasRelatedWork W2048760358 @default.
- W2067191737 hasRelatedWork W2067191737 @default.
- W2067191737 hasRelatedWork W2110566645 @default.
- W2067191737 hasRelatedWork W2128743891 @default.
- W2067191737 hasRelatedWork W2189322842 @default.
- W2067191737 hasRelatedWork W2314376598 @default.
- W2067191737 hasRelatedWork W3211257765 @default.
- W2067191737 hasVolume "215" @default.
- W2067191737 isParatext "false" @default.
- W2067191737 isRetracted "false" @default.
- W2067191737 magId "2067191737" @default.
- W2067191737 workType "article" @default.