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- W2067202040 abstract "Abstract The changes in cerebral phosphorus metabolites, intracellular pH, and lactate during 30 min of complete global ischemia and 2 h of reperfusion were monitored by time‐shared 1 H and 31 P in vivo NMR spectroscopy in rats. After the induction of ischemia, intracellular pH decreased from 7.14 ± 0.01 to 6.32 ± 0.10, and lactate concentration increased from 1.6 ± 0.4 to 15.8 ± 2.5 μmol/g; ATP and phosphocreatine were totally depleted, while inorganic phosphate increased 715 ± 47%. Within 1 h after blood flow was restored, high‐energy phosphates and lactate levels had recovered close to baseline levels. The changes in intracellular pH and lactate levels during ischemia and reperfusion correlated Well." @default.
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- W2067202040 title "Cerebral metabolite dynamics during temporary complete ischemia in rats monitored by time-shared1h and31p nmr spectroscopy" @default.
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