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• W2067208528 abstract "Analysis of the hydrolysis products of DNA from young and adult animals showed an age-dependent increase of a modified base peak. The modified material was similar to that produced in calf thymus and normal bases irradiated with 60Co gamma rays in the presence of oxygen. However, the estimation of the amount of modified product by ultraviolet absorption and radioactive measurements showed that the modified component has an unusally high ultraviolet absorption. Ultraviolet absorption spectra of the modified component from DNA and its bases are quite similar. These results suggest that oxidative modification of DNA bases in animal liver has occured, and support the proposed DNA oxidation hypothesis for aging and carcinogenesis." @default.
• W2067208528 created "2016-06-24" @default.
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• W2067208528 date "1980-09-01" @default.
• W2067208528 modified "2023-09-27" @default.
• W2067208528 title "Base modification in adult animal liver DNA and similarity to radiation-induced base modification" @default.
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• W2067208528 doi "https://doi.org/10.1016/0006-291x(80)91406-0" @default.
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