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- W2067223669 abstract "Spleen cells (SC) from tumor-bearing mice and mice immunized with porcine myelin basic protein (MBP) reacted in vitro in E-rosette augmentation assays with MBP and certain of its constituent peptides. Peptides 1–115, 43–169, 64–83, 113–121, and 153–161 reacted significantly with both types of SC, while peptide 1–19 reacted only with SC from MBP-immunized mice. The phenomenon of specific inhibition of peptide reactivity by a moderate excess of a related protein was used to identify peptides as accessible epitopes of that protein. Peptide 113–121 was specifically inhibited by excess MBP when reacted with both types of SC, whereas peptide 64–83 was inhibited by excess MBP only when reacted with SC from MBP-immunized mice. These reactions suggest that the immunizing antigen in tumor-bearing mice is related to MBP but differs in epitopes associated with peptides 1–19 and 64–83." @default.
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- W2067223669 title "Cell-mediated immunoreactivity of tumor-bearing mice with myelin basic protein and related peptides" @default.
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- W2067223669 doi "https://doi.org/10.1016/0008-8749(86)90042-0" @default.
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