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- W2067228701 abstract "Exhaustive digestion of the 0.76 μm mini-circles of the kinetoplast DNA from Crithidia luciliae with endonuclease HapII yields at least 37 fragments with an added molecular weight of at least 24 · 106, i.e. about 16 times that of the mini-circle. The DNA isolated from cloned cells yields the same digestion pattern. Endonuclease EcoRI cuts only part of the mini-circles in each network. This proves that mini-circles are not homogeneous in sequence. Digestion of total kinetoplast DNA with HapII yields, in addition to the mini-circle fragments, 7 fragments with an added molecular weight of 16 · 106. We conclude that these are derived from a minor component of the network, with a higher sequence complexity than the mini-circles." @default.
- W2067228701 created "2016-06-24" @default.
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- W2067228701 date "1975-11-01" @default.
- W2067228701 modified "2023-10-02" @default.
- W2067228701 title "Sequence heterogeneity of the mini-circles of kinetoplast DNA of Crithidia luciliae and evidence for the presence of a component more complex than mini-circle DNA in the kinetoplast network" @default.
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- W2067228701 doi "https://doi.org/10.1016/0005-2787(75)90301-9" @default.
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