FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067275313> ?p ?o ?g. }

• W2067275313 endingPage "14" @default.
• W2067275313 startingPage "11" @default.
• W2067275313 abstract "To clarify the mechanisms and risk factors of methadone toxicity and to describe the findings of deaths related to methadone use Design Retrospective review of case notes in the records of the San Francisco Medical Examiner comparing the findings in cases where methadone was deemed the cause of death with findings in decedents where methadone was an incidental finding, and with 50 age-matched, disease and drug free, trauma victims.38 cases out of the 3317 processed by our office during 1997-1998 were identified in which methadone had been detected. Cases were mostly male 28/38 (74%) and white, 28/38 (74%). In 17 of 38 cases death was deemed to have been caused by methadone toxicity. For the group the mean blood methadone concentration for all 38 patients, was 957 ng/ml SD = .681, SE = .14). The mean blood concentration of the main methadone metabolite (EDDP) was 253 ng/ml, SD = 529 ng/ml, SE = .089. The mean ratio of methadone in the blood to EDDP in the blood was 13.6:1 Values were not significantly different between cases in which methadone toxicity was the cause of death and in those in which it was an incidental finding. Cocaine, or the cocaine metabolite benzoylecgonine, was detected in the blood or urine of 16/38 cases (42%); morphine in one-third (13/38) and methamphetamine in only one. Pulmonary edema was evident in all cases, coronary artery disease in 9/38 (24%) and cirrhosis in 7/38 (18%) of the methadone users. Necrotizing fasciitis was the cause of death in 4 of the 38 methadone users (11%). Nationally, a sizeable percent of methadone deaths are from drugs diverted from treatment programs.The presence of methadone is often an incidental finding during postmortem examination which is unrelated to the cause of death. Postmortem measurements of methadone or its metabolite, or both, cannot be used in isolation to identify which deaths are associated with methadone toxicity." @default.
• W2067275313 created "2016-06-24" @default.
• W2067275313 creator A5051063580 @default.
• W2067275313 creator A5080777947 @default.
• W2067275313 date "2000-01-01" @default.
• W2067275313 modified "2023-09-23" @default.
• W2067275313 title "Toxicology and pathology of deaths related to methadone: retrospective review" @default.
• W2067275313 cites W1494031902 @default.
• W2067275313 cites W1499815876 @default.
• W2067275313 cites W1870043436 @default.
• W2067275313 cites W1979339835 @default.
• W2067275313 cites W1980642380 @default.
• W2067275313 cites W2002965038 @default.
• W2067275313 cites W2012776104 @default.
• W2067275313 cites W2017491815 @default.
• W2067275313 cites W2027005693 @default.
• W2067275313 cites W2029906878 @default.
• W2067275313 cites W2036556343 @default.
• W2067275313 cites W2042467292 @default.
• W2067275313 cites W2081558294 @default.
• W2067275313 cites W2093710070 @default.
• W2067275313 cites W2102383390 @default.
• W2067275313 cites W2103241463 @default.
• W2067275313 cites W2109597925 @default.
• W2067275313 cites W2220143414 @default.
• W2067275313 cites W2260149013 @default.
• W2067275313 cites W2333637006 @default.
• W2067275313 cites W2333750047 @default.
• W2067275313 cites W2406713751 @default.
• W2067275313 cites W2599954746 @default.
• W2067275313 doi "https://doi.org/10.1136/ewjm.172.1.11" @default.
• W2067275313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1070708" @default.
• W2067275313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10695434" @default.
• W2067275313 hasPublicationYear "2000" @default.
• W2067275313 type Work @default.
• W2067275313 sameAs 2067275313 @default.
• W2067275313 citedByCount "75" @default.
• W2067275313 countsByYear W20672753132012 @default.
• W2067275313 countsByYear W20672753132013 @default.
• W2067275313 countsByYear W20672753132014 @default.
• W2067275313 countsByYear W20672753132015 @default.
• W2067275313 countsByYear W20672753132016 @default.
• W2067275313 countsByYear W20672753132017 @default.
• W2067275313 countsByYear W20672753132019 @default.
• W2067275313 countsByYear W20672753132020 @default.
• W2067275313 countsByYear W20672753132021 @default.
• W2067275313 countsByYear W20672753132022 @default.
• W2067275313 countsByYear W20672753132023 @default.
• W2067275313 crossrefType "journal-article" @default.
• W2067275313 hasAuthorship W2067275313A5051063580 @default.
• W2067275313 hasAuthorship W2067275313A5080777947 @default.
• W2067275313 hasBestOaLocation W20672753132 @default.
• W2067275313 hasConcept C126322002 @default.
• W2067275313 hasConcept C167135981 @default.
• W2067275313 hasConcept C2777477808 @default.
• W2067275313 hasConcept C2777537440 @default.
• W2067275313 hasConcept C2778767360 @default.
• W2067275313 hasConcept C2778903686 @default.
• W2067275313 hasConcept C2780035454 @default.
• W2067275313 hasConcept C42219234 @default.
• W2067275313 hasConcept C71924100 @default.
• W2067275313 hasConcept C98274493 @default.
• W2067275313 hasConceptScore W2067275313C126322002 @default.
• W2067275313 hasConceptScore W2067275313C167135981 @default.
• W2067275313 hasConceptScore W2067275313C2777477808 @default.
• W2067275313 hasConceptScore W2067275313C2777537440 @default.
• W2067275313 hasConceptScore W2067275313C2778767360 @default.
• W2067275313 hasConceptScore W2067275313C2778903686 @default.
• W2067275313 hasConceptScore W2067275313C2780035454 @default.
• W2067275313 hasConceptScore W2067275313C42219234 @default.
• W2067275313 hasConceptScore W2067275313C71924100 @default.
• W2067275313 hasConceptScore W2067275313C98274493 @default.
• W2067275313 hasIssue "1" @default.
• W2067275313 hasLocation W20672753131 @default.
• W2067275313 hasLocation W20672753132 @default.
• W2067275313 hasLocation W20672753133 @default.
• W2067275313 hasLocation W20672753134 @default.
• W2067275313 hasOpenAccess W2067275313 @default.
• W2067275313 hasPrimaryLocation W20672753131 @default.
• W2067275313 hasRelatedWork W1788292798 @default.
• W2067275313 hasRelatedWork W1974563472 @default.
• W2067275313 hasRelatedWork W1998780861 @default.
• W2067275313 hasRelatedWork W2021936119 @default.
• W2067275313 hasRelatedWork W2081497085 @default.
• W2067275313 hasRelatedWork W2131956424 @default.
• W2067275313 hasRelatedWork W2137058576 @default.
• W2067275313 hasRelatedWork W2142146860 @default.
• W2067275313 hasRelatedWork W2145168763 @default.
• W2067275313 hasRelatedWork W3203875733 @default.
• W2067275313 hasVolume "172" @default.
• W2067275313 isParatext "false" @default.
• W2067275313 isRetracted "false" @default.
• W2067275313 magId "2067275313" @default.
• W2067275313 workType "article" @default.