Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067343408> ?p ?o ?g. }
- W2067343408 endingPage "29" @default.
- W2067343408 startingPage "20" @default.
- W2067343408 abstract "Venlafaxine (Effexor) is an effective antidepressant and has also been approved for the treatment of generalized anxiety disorder. Venlafaxine was initially characterized as an inhibitor of both serotonin (5HT) and norepinephrine (NE) uptake and was therefore termed a dual uptake inhibitor. This chapter reviews data from both in vitro and in vivo studies regarding its effects on 5HT and NE neurotransmission. In addition, the effects of venlafaxine on other systems that may play a role in its therapeutic efficacy effects are described. The data indicate that venlafaxine is a relatively weak inhibitor of NE transport in vitro. In vivo studies indicate that venlafaxine selectively inhibits 5HT uptake at low therapeutic doses and inhibits both 5HT and NE uptake at higher therapeutic doses. This chapter concludes with a discussion of the effects of venlafaxine on various aspects of physiology." @default.
- W2067343408 created "2016-06-24" @default.
- W2067343408 creator A5062318456 @default.
- W2067343408 creator A5073006707 @default.
- W2067343408 date "2000-01-01" @default.
- W2067343408 modified "2023-10-10" @default.
- W2067343408 title "Neuropharmacology of venlafaxine" @default.
- W2067343408 cites W1483255595 @default.
- W2067343408 cites W1542427252 @default.
- W2067343408 cites W1567238908 @default.
- W2067343408 cites W1964290815 @default.
- W2067343408 cites W1966747636 @default.
- W2067343408 cites W1968083735 @default.
- W2067343408 cites W1970421748 @default.
- W2067343408 cites W1971008362 @default.
- W2067343408 cites W1975377762 @default.
- W2067343408 cites W1975588016 @default.
- W2067343408 cites W1976481607 @default.
- W2067343408 cites W1979231092 @default.
- W2067343408 cites W1979293025 @default.
- W2067343408 cites W1980307974 @default.
- W2067343408 cites W1986242073 @default.
- W2067343408 cites W1989007151 @default.
- W2067343408 cites W1989699877 @default.
- W2067343408 cites W1990917297 @default.
- W2067343408 cites W1991498591 @default.
- W2067343408 cites W1992631164 @default.
- W2067343408 cites W1994993200 @default.
- W2067343408 cites W2000639093 @default.
- W2067343408 cites W2004080775 @default.
- W2067343408 cites W2005020005 @default.
- W2067343408 cites W2006880154 @default.
- W2067343408 cites W2013273844 @default.
- W2067343408 cites W2013680238 @default.
- W2067343408 cites W2016565752 @default.
- W2067343408 cites W2020659371 @default.
- W2067343408 cites W2021665391 @default.
- W2067343408 cites W2023754866 @default.
- W2067343408 cites W2031134409 @default.
- W2067343408 cites W2032099586 @default.
- W2067343408 cites W2036081896 @default.
- W2067343408 cites W2037016869 @default.
- W2067343408 cites W2037662525 @default.
- W2067343408 cites W2038875755 @default.
- W2067343408 cites W2040921498 @default.
- W2067343408 cites W2042360481 @default.
- W2067343408 cites W2043363666 @default.
- W2067343408 cites W2046470449 @default.
- W2067343408 cites W2047121031 @default.
- W2067343408 cites W2051531767 @default.
- W2067343408 cites W2058396341 @default.
- W2067343408 cites W2063074934 @default.
- W2067343408 cites W2066094303 @default.
- W2067343408 cites W2069970023 @default.
- W2067343408 cites W2071289233 @default.
- W2067343408 cites W2071765053 @default.
- W2067343408 cites W2072524174 @default.
- W2067343408 cites W2073432994 @default.
- W2067343408 cites W2074385687 @default.
- W2067343408 cites W2077085632 @default.
- W2067343408 cites W2079858963 @default.
- W2067343408 cites W2082154403 @default.
- W2067343408 cites W2083659148 @default.
- W2067343408 cites W2083696055 @default.
- W2067343408 cites W2083783723 @default.
- W2067343408 cites W2085525314 @default.
- W2067343408 cites W2087237399 @default.
- W2067343408 cites W2092114190 @default.
- W2067343408 cites W2092377028 @default.
- W2067343408 cites W2092399682 @default.
- W2067343408 cites W2093191371 @default.
- W2067343408 cites W2094330039 @default.
- W2067343408 cites W2095253451 @default.
- W2067343408 cites W2097097294 @default.
- W2067343408 cites W2110183017 @default.
- W2067343408 cites W2143629083 @default.
- W2067343408 cites W2143959809 @default.
- W2067343408 cites W2151408723 @default.
- W2067343408 cites W2167193786 @default.
- W2067343408 cites W2321488592 @default.
- W2067343408 cites W4244778838 @default.
- W2067343408 doi "https://doi.org/10.1002/1520-6394(2000)12:1+<20::aid-da3>3.0.co;2-m" @default.
- W2067343408 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11098411" @default.
- W2067343408 hasPublicationYear "2000" @default.
- W2067343408 type Work @default.
- W2067343408 sameAs 2067343408 @default.
- W2067343408 citedByCount "43" @default.
- W2067343408 countsByYear W20673434082012 @default.
- W2067343408 countsByYear W20673434082013 @default.
- W2067343408 countsByYear W20673434082014 @default.
- W2067343408 countsByYear W20673434082015 @default.
- W2067343408 countsByYear W20673434082016 @default.
- W2067343408 countsByYear W20673434082017 @default.
- W2067343408 countsByYear W20673434082022 @default.
- W2067343408 countsByYear W20673434082023 @default.
- W2067343408 crossrefType "journal-article" @default.
- W2067343408 hasAuthorship W2067343408A5062318456 @default.
- W2067343408 hasAuthorship W2067343408A5073006707 @default.