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- W2067352893 abstract "Objective The aim of the present study was to evaluate the effects of β-tricalcium phosphate/carboxymethyl-chitin material (β-TCP/CM-chitin) on bone formation in rat calvarial defects. Study Design Eighteen animals surgically received 2 calvarial defects (5 mm) bilaterally in each parietal bone. β-TCP/CM-chitin was implanted in one side of each defect, and the contralateral side of the defect was left empty as a control. The animals were humanely killed at 4, 8, and 12 weeks after surgery for histologic evaluation. Results New bone formation in the β-TCP/CM-chitin group was significantly greater than that in the control group throughout the healing periods (P < .05). β-TCP/CM-chitin was remarkably resorbed 12 weeks after surgery. Conclusions These results indicate that β-TCP/CM-chitin is useful as a scaffold for bone formation. The aim of the present study was to evaluate the effects of β-tricalcium phosphate/carboxymethyl-chitin material (β-TCP/CM-chitin) on bone formation in rat calvarial defects. Eighteen animals surgically received 2 calvarial defects (5 mm) bilaterally in each parietal bone. β-TCP/CM-chitin was implanted in one side of each defect, and the contralateral side of the defect was left empty as a control. The animals were humanely killed at 4, 8, and 12 weeks after surgery for histologic evaluation. New bone formation in the β-TCP/CM-chitin group was significantly greater than that in the control group throughout the healing periods (P < .05). β-TCP/CM-chitin was remarkably resorbed 12 weeks after surgery. These results indicate that β-TCP/CM-chitin is useful as a scaffold for bone formation." @default.
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- W2067352893 date "2013-12-01" @default.
- W2067352893 modified "2023-09-26" @default.
- W2067352893 title "Bone formation using β-tricalcium phosphate/carboxymethyl-chitin composite scaffold in rat calvarial defects" @default.
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- W2067352893 doi "https://doi.org/10.1016/j.oooo.2012.02.033" @default.
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