Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067392502> ?p ?o ?g. }
- W2067392502 endingPage "113" @default.
- W2067392502 startingPage "97" @default.
- W2067392502 abstract "Activated platelets contribute to plaque formation within blood vessels in the early and late stages of atherogenesis, and therefore they have been proposed as risk factor for cardiovascular disease. Anti-platelet drugs, such as aspirin, are now the most prescribed pharmacological treatment in Europe. Certain dietary bioactives also beneficially affect platelet function, and with less side effects, albeit that effects are generally more subtle. Therefore, consumption of dietary bioactives could play a role in the prevention of atherothrombotic vascular disease. Here we review the efficacy of dietary treatment strategies, especially those involving certain dietary fatty acids and polyphenols, to modulate platelet function in healthy subjects or in patients with cardiovascular disease. Variation in study populations, small study sizes and lack of comparability between methods to assess platelet function currently limit robust evidence on the efficacy of dietary bioactives in healthy subjects or specific patient groups. Also, limited knowledge of the metabolism of dietary bioactives, and therefore of the bioavailability of bioactive ingredients, restricts our ability to identify the most effective dietary regimes to improve platelet function. Implementation of uniform point-of-care tests to assess platelet function, and enhanced knowledge of the efficacy by which specific dietary compounds and their metabolites affect platelet function, may enable the identification of functional anti-platelet ingredients that are eligible for a health claim, or combined treatment strategies, including both pharmacological anti-platelet treatment as well as dietary intervention, to tackle atherothrombotic vascular disease." @default.
- W2067392502 created "2016-06-24" @default.
- W2067392502 creator A5035732845 @default.
- W2067392502 creator A5060417803 @default.
- W2067392502 creator A5061116453 @default.
- W2067392502 creator A5073985049 @default.
- W2067392502 date "2014-11-01" @default.
- W2067392502 modified "2023-10-13" @default.
- W2067392502 title "Dietary manipulation of platelet function" @default.
- W2067392502 cites W10734288 @default.
- W2067392502 cites W11128447 @default.
- W2067392502 cites W127902162 @default.
- W2067392502 cites W133668382 @default.
- W2067392502 cites W1493000949 @default.
- W2067392502 cites W1574732221 @default.
- W2067392502 cites W1577086711 @default.
- W2067392502 cites W1725912737 @default.
- W2067392502 cites W1795774420 @default.
- W2067392502 cites W181063792 @default.
- W2067392502 cites W1849728297 @default.
- W2067392502 cites W1865530734 @default.
- W2067392502 cites W1868589471 @default.
- W2067392502 cites W1895802579 @default.
- W2067392502 cites W1926128061 @default.
- W2067392502 cites W1967434490 @default.
- W2067392502 cites W1968358736 @default.
- W2067392502 cites W1969258566 @default.
- W2067392502 cites W1969828880 @default.
- W2067392502 cites W1972832497 @default.
- W2067392502 cites W1975308676 @default.
- W2067392502 cites W1976039425 @default.
- W2067392502 cites W1976516803 @default.
- W2067392502 cites W1977009898 @default.
- W2067392502 cites W1983061158 @default.
- W2067392502 cites W1984978682 @default.
- W2067392502 cites W1987481358 @default.
- W2067392502 cites W1987669517 @default.
- W2067392502 cites W1990065296 @default.
- W2067392502 cites W1990374802 @default.
- W2067392502 cites W1994704845 @default.
- W2067392502 cites W1995813452 @default.
- W2067392502 cites W1996401742 @default.
- W2067392502 cites W2000248987 @default.
- W2067392502 cites W2002493157 @default.
- W2067392502 cites W2003087572 @default.
- W2067392502 cites W2003347868 @default.
- W2067392502 cites W2003807667 @default.
- W2067392502 cites W2005487053 @default.
- W2067392502 cites W2006026172 @default.
- W2067392502 cites W2008770403 @default.
- W2067392502 cites W2009106946 @default.
- W2067392502 cites W2009264820 @default.
- W2067392502 cites W2011336591 @default.
- W2067392502 cites W2011485962 @default.
- W2067392502 cites W2011647087 @default.
- W2067392502 cites W2012214760 @default.
- W2067392502 cites W2015972877 @default.
- W2067392502 cites W2016229713 @default.
- W2067392502 cites W2017269547 @default.
- W2067392502 cites W2018278847 @default.
- W2067392502 cites W2018484402 @default.
- W2067392502 cites W2019410991 @default.
- W2067392502 cites W2021453562 @default.
- W2067392502 cites W2022825673 @default.
- W2067392502 cites W2022940452 @default.
- W2067392502 cites W2023823156 @default.
- W2067392502 cites W2023947664 @default.
- W2067392502 cites W2023995851 @default.
- W2067392502 cites W2030273921 @default.
- W2067392502 cites W2032600755 @default.
- W2067392502 cites W2033200351 @default.
- W2067392502 cites W2033962055 @default.
- W2067392502 cites W2034520153 @default.
- W2067392502 cites W2036945446 @default.
- W2067392502 cites W2039611770 @default.
- W2067392502 cites W2039750402 @default.
- W2067392502 cites W2039881470 @default.
- W2067392502 cites W2040651415 @default.
- W2067392502 cites W2042268348 @default.
- W2067392502 cites W2044123810 @default.
- W2067392502 cites W2047419091 @default.
- W2067392502 cites W2048570075 @default.
- W2067392502 cites W2050301982 @default.
- W2067392502 cites W2052547401 @default.
- W2067392502 cites W2052620776 @default.
- W2067392502 cites W2052694209 @default.
- W2067392502 cites W2053285808 @default.
- W2067392502 cites W2056284521 @default.
- W2067392502 cites W2057721190 @default.
- W2067392502 cites W2057838422 @default.
- W2067392502 cites W2058554950 @default.
- W2067392502 cites W2058593684 @default.
- W2067392502 cites W2059873285 @default.
- W2067392502 cites W2060563066 @default.
- W2067392502 cites W2062279965 @default.
- W2067392502 cites W2064114884 @default.
- W2067392502 cites W2064206046 @default.
- W2067392502 cites W2069866651 @default.