FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067412904> ?p ?o ?g. }

• W2067412904 endingPage "380" @default.
• W2067412904 startingPage "367" @default.
• W2067412904 abstract "Exposure to polychlorinated biphenyls (PCBs) during pre-natal and early life can alter normal immune system development. Blood specimens from newborns, 6-, and 16-month-old infants were collected in the Michalovce and Svidnik/Stropkov districts, areas with, respectively, high and low environmental PCB contamination, and lymphocyte receptor expression was evaluated by multi-color flow cytometry. The results indicate that the percentage of lymphoid dendritic cells (DC) and naïve/resting T-lymphocytes were significantly increased at 6-months in Michalovce as compared to the same cell types in cord blood samples (p < 0.001), whereas natural regulatory T-lymphocytes and suppressor inducer T-lymphocytes were reduced (p < 0.001). Overall, a positive linear correlation of terminally differentiated effector memory (TEM) T-lymphocyte population with age, but a negative linear correlation for myeloid DC from birth to 6-months in both regions were found. Michalovce samples indicated significantly higher expression of memory T-lymphocytes (birth, 6th, and 16th month), TEM T-lymphocytes (birth and 6th month), and lymphoid DC (6th month) compared to the Svidnik/Stropkov regions. After adjustment for relevant covariates, such as maternal age, parity, season of birth, breastfeeding, birth weight, and gender, the myeloid DC, suppressor inducer T-lymphocytes, truly naïve helper/inducer T-lymphocytes, and TEM T-lymphocytes remained significantly different between districts in cord blood samples. The multivariate analysis models for 6- and 16-month samples showed district differences in all cellular determinants, except for lymphoid DC and macrophage-like cells. This study provides the first evidence that pre-natal and early post-natal exposure to PCBs affects the dynamics of cell surface receptor expression on lymphoid DC and DC-like cells, suggesting impaired immunologic development following pre-natal and early post-natal PCB exposure." @default.
• W2067412904 created "2016-06-24" @default.
• W2067412904 creator A5023956040 @default.
• W2067412904 creator A5036566793 @default.
• W2067412904 creator A5049657813 @default.
• W2067412904 creator A5056795123 @default.
• W2067412904 creator A5073062370 @default.
• W2067412904 date "2011-11-02" @default.
• W2067412904 modified "2023-09-27" @default.
• W2067412904 title "The kinetics of cell surface receptor expression in children perinatally exposed to polychlorinated biphenyls" @default.
• W2067412904 cites W1561046927 @default.
• W2067412904 cites W1674610324 @default.
• W2067412904 cites W17966201 @default.
• W2067412904 cites W1967319699 @default.
• W2067412904 cites W1976697134 @default.
• W2067412904 cites W1986790722 @default.
• W2067412904 cites W1991557893 @default.
• W2067412904 cites W1993310853 @default.
• W2067412904 cites W2003239307 @default.
• W2067412904 cites W2004141379 @default.
• W2067412904 cites W2004401987 @default.
• W2067412904 cites W2007367923 @default.
• W2067412904 cites W2008498033 @default.
• W2067412904 cites W2023068131 @default.
• W2067412904 cites W2028055317 @default.
• W2067412904 cites W2032155611 @default.
• W2067412904 cites W2035944097 @default.
• W2067412904 cites W2043551077 @default.
• W2067412904 cites W2062347276 @default.
• W2067412904 cites W2065138489 @default.
• W2067412904 cites W2076282701 @default.
• W2067412904 cites W2082015887 @default.
• W2067412904 cites W2096355705 @default.
• W2067412904 cites W2097193479 @default.
• W2067412904 cites W2105306090 @default.
• W2067412904 cites W2115651087 @default.
• W2067412904 cites W2118107779 @default.
• W2067412904 cites W2123402179 @default.
• W2067412904 cites W2130491816 @default.
• W2067412904 cites W2140764858 @default.
• W2067412904 cites W2142417041 @default.
• W2067412904 cites W2146912985 @default.
• W2067412904 cites W2152407385 @default.
• W2067412904 cites W2153339313 @default.
• W2067412904 cites W2168787849 @default.
• W2067412904 cites W2433059305 @default.
• W2067412904 doi "https://doi.org/10.3109/1547691x.2011.620037" @default.
• W2067412904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22047017" @default.
• W2067412904 hasPublicationYear "2011" @default.
• W2067412904 type Work @default.
• W2067412904 sameAs 2067412904 @default.
• W2067412904 citedByCount "9" @default.
• W2067412904 countsByYear W20674129042013 @default.
• W2067412904 countsByYear W20674129042014 @default.
• W2067412904 countsByYear W20674129042015 @default.
• W2067412904 countsByYear W20674129042016 @default.
• W2067412904 countsByYear W20674129042017 @default.
• W2067412904 countsByYear W20674129042019 @default.
• W2067412904 countsByYear W20674129042021 @default.
• W2067412904 crossrefType "journal-article" @default.
• W2067412904 hasAuthorship W2067412904A5023956040 @default.
• W2067412904 hasAuthorship W2067412904A5036566793 @default.
• W2067412904 hasAuthorship W2067412904A5049657813 @default.
• W2067412904 hasAuthorship W2067412904A5056795123 @default.
• W2067412904 hasAuthorship W2067412904A5073062370 @default.
• W2067412904 hasBestOaLocation W20674129041 @default.
• W2067412904 hasConcept C104317684 @default.
• W2067412904 hasConcept C126322002 @default.
• W2067412904 hasConcept C134018914 @default.
• W2067412904 hasConcept C16685009 @default.
• W2067412904 hasConcept C203014093 @default.
• W2067412904 hasConcept C2225953 @default.
• W2067412904 hasConcept C2777761686 @default.
• W2067412904 hasConcept C2779282312 @default.
• W2067412904 hasConcept C2780914630 @default.
• W2067412904 hasConcept C2908647359 @default.
• W2067412904 hasConcept C2992881475 @default.
• W2067412904 hasConcept C54355233 @default.
• W2067412904 hasConcept C553184892 @default.
• W2067412904 hasConcept C71924100 @default.
• W2067412904 hasConcept C86803240 @default.
• W2067412904 hasConcept C8891405 @default.
• W2067412904 hasConcept C99454951 @default.
• W2067412904 hasConceptScore W2067412904C104317684 @default.
• W2067412904 hasConceptScore W2067412904C126322002 @default.
• W2067412904 hasConceptScore W2067412904C134018914 @default.
• W2067412904 hasConceptScore W2067412904C16685009 @default.
• W2067412904 hasConceptScore W2067412904C203014093 @default.
• W2067412904 hasConceptScore W2067412904C2225953 @default.
• W2067412904 hasConceptScore W2067412904C2777761686 @default.
• W2067412904 hasConceptScore W2067412904C2779282312 @default.
• W2067412904 hasConceptScore W2067412904C2780914630 @default.
• W2067412904 hasConceptScore W2067412904C2908647359 @default.
• W2067412904 hasConceptScore W2067412904C2992881475 @default.
• W2067412904 hasConceptScore W2067412904C54355233 @default.
• W2067412904 hasConceptScore W2067412904C553184892 @default.
• W2067412904 hasConceptScore W2067412904C71924100 @default.
• W2067412904 hasConceptScore W2067412904C86803240 @default.

• next