FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067442826> ?p ?o ?g. }

• W2067442826 endingPage "2246" @default.
• W2067442826 startingPage "2238" @default.
• W2067442826 abstract "Synaptic membrane fusion, which is necessary for neurotransmitter release, may be mediated by SNAREs and regulated by synaptotagmin (Syt) and Ca 2+ . Fusion of liposomes mediated by reconstituted SNAREs produces full fusion and hemifusion, a membrane structure in which outer leaflets are mixed but the inner leaflets remain intact. Here, using the liposome fusion assay, it is shown that Syt promoted both hemifusion and full fusion in a Ca 2+ ‐dependent manner. Syt · Ca 2+ increased hemifusion more than full fusion, modulating the ratio of hemifusion to full fusion. Unlike the case of neuronal SNAREs, stimulation of fusion by Syt · Ca 2+ was not seen for other SNAREs involved in trafficking in yeast, indicating that the Syt · Ca 2+ stimulation was SNARE‐specific. We constructed hybrid SNAREs in which transmembrane domains were swapped between neuronal and yeast SNAREs. With these hybrid SNAREs, we demonstrated that the interaction between the SNARE motifs of neuronal proteins and Syt · Ca 2+ was required for the stimulation of fusion." @default.
• W2067442826 created "2016-06-24" @default.
• W2067442826 creator A5007579590 @default.
• W2067442826 creator A5053447705 @default.
• W2067442826 creator A5054947471 @default.
• W2067442826 creator A5088267976 @default.
• W2067442826 date "2006-03-20" @default.
• W2067442826 modified "2023-10-17" @default.
• W2067442826 title "Synaptotagmin I and Ca²⁺promote half fusion more than full fusion in SNARE-mediated bilayer fusion" @default.
• W2067442826 cites W1564650596 @default.
• W2067442826 cites W1591133722 @default.
• W2067442826 cites W1822252127 @default.
• W2067442826 cites W1964770089 @default.
• W2067442826 cites W1967141060 @default.
• W2067442826 cites W1967817609 @default.
• W2067442826 cites W1968301751 @default.
• W2067442826 cites W1968563729 @default.
• W2067442826 cites W1970930136 @default.
• W2067442826 cites W1971016259 @default.
• W2067442826 cites W1976283234 @default.
• W2067442826 cites W1977017692 @default.
• W2067442826 cites W1990630751 @default.
• W2067442826 cites W1994218245 @default.
• W2067442826 cites W1995528444 @default.
• W2067442826 cites W1996704622 @default.
• W2067442826 cites W1999213641 @default.
• W2067442826 cites W2001389730 @default.
• W2067442826 cites W2008146383 @default.
• W2067442826 cites W2009417622 @default.
• W2067442826 cites W2015611396 @default.
• W2067442826 cites W2016266703 @default.
• W2067442826 cites W2020593055 @default.
• W2067442826 cites W2030987020 @default.
• W2067442826 cites W2031948819 @default.
• W2067442826 cites W2035827727 @default.
• W2067442826 cites W2037702696 @default.
• W2067442826 cites W2044679183 @default.
• W2067442826 cites W2048172776 @default.
• W2067442826 cites W2049308967 @default.
• W2067442826 cites W2052999464 @default.
• W2067442826 cites W2056293200 @default.
• W2067442826 cites W2061312580 @default.
• W2067442826 cites W2076386790 @default.
• W2067442826 cites W2079405491 @default.
• W2067442826 cites W2082832485 @default.
• W2067442826 cites W2085680244 @default.
• W2067442826 cites W2086696756 @default.
• W2067442826 cites W2086890785 @default.
• W2067442826 cites W2096582689 @default.
• W2067442826 cites W2101027975 @default.
• W2067442826 cites W2114795136 @default.
• W2067442826 cites W2115053775 @default.
• W2067442826 cites W2116866168 @default.
• W2067442826 cites W2118639186 @default.
• W2067442826 cites W2123151328 @default.
• W2067442826 cites W2123355036 @default.
• W2067442826 cites W2129430733 @default.
• W2067442826 cites W2136537803 @default.
• W2067442826 cites W2146184846 @default.
• W2067442826 cites W2154100802 @default.
• W2067442826 cites W2154649008 @default.
• W2067442826 cites W4210958643 @default.
• W2067442826 cites W4242451072 @default.
• W2067442826 doi "https://doi.org/10.1016/j.febslet.2006.03.035" @default.
• W2067442826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16566927" @default.
• W2067442826 hasPublicationYear "2006" @default.
• W2067442826 type Work @default.
• W2067442826 sameAs 2067442826 @default.
• W2067442826 citedByCount "25" @default.
• W2067442826 countsByYear W20674428262012 @default.
• W2067442826 countsByYear W20674428262015 @default.
• W2067442826 countsByYear W20674428262017 @default.
• W2067442826 countsByYear W20674428262018 @default.
• W2067442826 crossrefType "journal-article" @default.
• W2067442826 hasAuthorship W2067442826A5007579590 @default.
• W2067442826 hasAuthorship W2067442826A5053447705 @default.
• W2067442826 hasAuthorship W2067442826A5054947471 @default.
• W2067442826 hasAuthorship W2067442826A5088267976 @default.
• W2067442826 hasBestOaLocation W20674428261 @default.
• W2067442826 hasConcept C103038307 @default.
• W2067442826 hasConcept C12554922 @default.
• W2067442826 hasConcept C130316041 @default.
• W2067442826 hasConcept C134499376 @default.
• W2067442826 hasConcept C138885662 @default.
• W2067442826 hasConcept C148785051 @default.
• W2067442826 hasConcept C158525013 @default.
• W2067442826 hasConcept C170493617 @default.
• W2067442826 hasConcept C185592680 @default.
• W2067442826 hasConcept C196330066 @default.
• W2067442826 hasConcept C24530287 @default.
• W2067442826 hasConcept C2908790754 @default.
• W2067442826 hasConcept C2909695770 @default.
• W2067442826 hasConcept C41625074 @default.
• W2067442826 hasConcept C41895202 @default.
• W2067442826 hasConcept C55493867 @default.
• W2067442826 hasConcept C86473631 @default.
• W2067442826 hasConcept C86803240 @default.
• W2067442826 hasConcept C95444343 @default.

• next