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• W2067446011 abstract "While traditionally recognized for their roles in hemostatic pathways, emerging evidence demonstrates that platelets have previously unrecognized, dynamic roles that span the immune continuum. These newly recognized platelet functions, including the secretion of immune mediators, interactions with endothelial cells, monocytes, and neutrophils, toll-like receptor (TLR) mediated responses, and induction of neutrophil extracellular trap formation, bridge thrombotic and inflammatory pathways and contribute to host defense mechanisms against invading pathogens. In this focused review, we highlight several of these emerging aspects of platelet biology and their implications in clinical infectious syndromes." @default.
• W2067446011 created "2016-06-24" @default.
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• W2067446011 date "2014-12-18" @default.
• W2067446011 modified "2023-09-26" @default.
• W2067446011 title "Emerging Evidence for Platelets as Immune and Inflammatory Effector Cells" @default.
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• W2067446011 doi "https://doi.org/10.3389/fimmu.2014.00653" @default.
• W2067446011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4270189" @default.
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