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• W2067477675 startingPage "2392" @default.
• W2067477675 abstract "The complex and yet unknown etiology of Crohn's disease (CD) might consist of various disease endophenotypes, each of which represent their own pathogenesis. This review focuses on the disease endophenotype linked to polymorphisms in the nucleotide-binding oligomerization domain containing 2 (NOD2) protein and on the importance of established adherent-invasive E. coli (AIEC) in ileal mucosa. To date, there are several reports pointing to the implications of NOD2 polymorphisms in epithelial and immunological responses against microbes, but the pathological significance of NOD2 mutations in CD is not yet clarified. The enhanced number of pathogenic E. coli in the ileal mucosa of CD as compared to healthy controls may result from a genetically based failure in one of the intestinal bacteria sensing systems, like NOD2, making the ileal epithelium more prone to colonization with microbes harboring specific properties such as AIEC. Increasing the focus on defining subgroups of patients with similar disease initiations, mechanisms of action, and manifestations in CD may be pivotal for the development and implementation of future individualized treatment strategies of benefit for the single patient at an early stage." @default.
• W2067477675 created "2016-06-24" @default.
• W2067477675 creator A5008574018 @default.
• W2067477675 creator A5029735205 @default.
• W2067477675 creator A5081281256 @default.
• W2067477675 date "2011-11-01" @default.
• W2067477675 modified "2023-09-23" @default.
• W2067477675 title "Are NOD2 polymorphisms linked to a specific disease endophenotype of Crohnʼs disease?" @default.
• W2067477675 cites W1568874426 @default.
• W2067477675 cites W1642457845 @default.
• W2067477675 cites W1670573097 @default.
• W2067477675 cites W1964718835 @default.
• W2067477675 cites W1969767037 @default.
• W2067477675 cites W1971046821 @default.
• W2067477675 cites W1972672220 @default.
• W2067477675 cites W1979859398 @default.
• W2067477675 cites W1981714996 @default.
• W2067477675 cites W1985508783 @default.
• W2067477675 cites W1986082405 @default.
• W2067477675 cites W1991625690 @default.
• W2067477675 cites W1995321760 @default.
• W2067477675 cites W1997146138 @default.
• W2067477675 cites W1998395322 @default.
• W2067477675 cites W1999112936 @default.
• W2067477675 cites W2006773330 @default.
• W2067477675 cites W2009706335 @default.
• W2067477675 cites W2011197968 @default.
• W2067477675 cites W2018542503 @default.
• W2067477675 cites W2018544780 @default.
• W2067477675 cites W2020630498 @default.
• W2067477675 cites W2021839438 @default.
• W2067477675 cites W2024831496 @default.
• W2067477675 cites W2025184453 @default.
• W2067477675 cites W2026074634 @default.
• W2067477675 cites W2036188131 @default.
• W2067477675 cites W2036677443 @default.
• W2067477675 cites W2038343076 @default.
• W2067477675 cites W2040780867 @default.
• W2067477675 cites W2041170922 @default.
• W2067477675 cites W2042675697 @default.
• W2067477675 cites W2042878747 @default.
• W2067477675 cites W2043667001 @default.
• W2067477675 cites W2043775908 @default.
• W2067477675 cites W2045826544 @default.
• W2067477675 cites W2047059509 @default.
• W2067477675 cites W2052127995 @default.
• W2067477675 cites W2054602599 @default.
• W2067477675 cites W2057610674 @default.
• W2067477675 cites W2057944830 @default.
• W2067477675 cites W2060447010 @default.
• W2067477675 cites W2064027072 @default.
• W2067477675 cites W2064432044 @default.
• W2067477675 cites W2068233027 @default.
• W2067477675 cites W2071366086 @default.
• W2067477675 cites W2072364434 @default.
• W2067477675 cites W2073731887 @default.
• W2067477675 cites W2073869570 @default.
• W2067477675 cites W2075583035 @default.
• W2067477675 cites W2077604052 @default.
• W2067477675 cites W2086607027 @default.
• W2067477675 cites W2092347839 @default.
• W2067477675 cites W2095342336 @default.
• W2067477675 cites W2097121808 @default.
• W2067477675 cites W2097177097 @default.
• W2067477675 cites W2097875133 @default.
• W2067477675 cites W2102764783 @default.
• W2067477675 cites W2104160845 @default.
• W2067477675 cites W2105190780 @default.
• W2067477675 cites W2107066107 @default.
• W2067477675 cites W2110372095 @default.
• W2067477675 cites W2111900042 @default.
• W2067477675 cites W2112567807 @default.
• W2067477675 cites W2115207445 @default.
• W2067477675 cites W2116034738 @default.
• W2067477675 cites W2116242225 @default.
• W2067477675 cites W2118283102 @default.
• W2067477675 cites W2125826054 @default.
• W2067477675 cites W2126358235 @default.
• W2067477675 cites W2129035113 @default.
• W2067477675 cites W2134783591 @default.
• W2067477675 cites W2135100507 @default.
• W2067477675 cites W2138651252 @default.
• W2067477675 cites W2151817818 @default.
• W2067477675 cites W2153130127 @default.
• W2067477675 cites W2153905079 @default.
• W2067477675 cites W2158224200 @default.
• W2067477675 cites W2158364865 @default.
• W2067477675 cites W2163197066 @default.
• W2067477675 cites W2165279431 @default.
• W2067477675 cites W2169909966 @default.
• W2067477675 cites W2773388190 @default.
• W2067477675 cites W4231022815 @default.
• W2067477675 doi "https://doi.org/10.1002/ibd.21656" @default.
• W2067477675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21337670" @default.
• W2067477675 hasPublicationYear "2011" @default.
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