Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067492711> ?p ?o ?g. }
- W2067492711 endingPage "228" @default.
- W2067492711 startingPage "213" @default.
- W2067492711 abstract "Using an immunoadsorbent column conjugated with anti-macrophage chemotactic factor-c (anti-MCF-c), MCF-c which has been separated and highly purified from a delayed-type hypersensitivity reaction (DHR) site, shares common antigenicity with the major macrophage chemotactic lymphokine released from purified protein derivative (PPD)-stimulated lymphocytes and also macrophage chemotactic lymphokine from phytohemagglutinin (PHA)-stimulated lymphocytes. Using a combination of the immunoadsorbent column and Sephadexgel chromatography these two lymphokines are purified to homogeneity from PPD- or PHA-stimulated guinea pig lymphocyte culture supernatants. These observations, taken in conjunction with the similarity in biological activities, physicochemical properties, and antigenicities, suggest that these two mediators are very similar, or possibly identical. MCF-c with chemotactic activity for macrophages seemed to exist as complexes with serum protein at the skin site of PPD-induced DHR in guinea pigs. The active substance, separated from the complexes under acid conditions, is indistinguishable from the major macrophage chemotactic lymphokine released by PPD stimulation with respect to antigenicity, heat stability, and non-diffusibility. They both have a molecular weight of about 12, 500. The chemotactic lymphokine formed comparable complexes with serum protein under neutral conditions; however, this complex dissociated in acid without loss of activity." @default.
- W2067492711 created "2016-06-24" @default.
- W2067492711 creator A5030451301 @default.
- W2067492711 creator A5041069711 @default.
- W2067492711 creator A5044791422 @default.
- W2067492711 creator A5063917475 @default.
- W2067492711 date "1982-03-01" @default.
- W2067492711 modified "2023-10-16" @default.
- W2067492711 title "Characterization of a macrophage chemotactic lymphokine produced by purified protein derivative stimulation in vitro and in vivo" @default.
- W2067492711 cites W1552499690 @default.
- W2067492711 cites W1553879259 @default.
- W2067492711 cites W1566843496 @default.
- W2067492711 cites W1579782678 @default.
- W2067492711 cites W1581195721 @default.
- W2067492711 cites W1593110487 @default.
- W2067492711 cites W1822783585 @default.
- W2067492711 cites W1898407417 @default.
- W2067492711 cites W1946681269 @default.
- W2067492711 cites W1975324815 @default.
- W2067492711 cites W1975989837 @default.
- W2067492711 cites W1987446470 @default.
- W2067492711 cites W1997075444 @default.
- W2067492711 cites W2008396790 @default.
- W2067492711 cites W2016102216 @default.
- W2067492711 cites W2018377262 @default.
- W2067492711 cites W2037346389 @default.
- W2067492711 cites W2039205268 @default.
- W2067492711 cites W2039303658 @default.
- W2067492711 cites W2041552435 @default.
- W2067492711 cites W2061594339 @default.
- W2067492711 cites W2078487105 @default.
- W2067492711 cites W2101019091 @default.
- W2067492711 cites W2104356293 @default.
- W2067492711 cites W2132068224 @default.
- W2067492711 cites W256088527 @default.
- W2067492711 cites W4313309129 @default.
- W2067492711 cites W4313310866 @default.
- W2067492711 cites W4313310979 @default.
- W2067492711 cites W4313376314 @default.
- W2067492711 cites W962351851 @default.
- W2067492711 doi "https://doi.org/10.1016/0008-8749(82)90215-5" @default.
- W2067492711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7044572" @default.
- W2067492711 hasPublicationYear "1982" @default.
- W2067492711 type Work @default.
- W2067492711 sameAs 2067492711 @default.
- W2067492711 citedByCount "23" @default.
- W2067492711 crossrefType "journal-article" @default.
- W2067492711 hasAuthorship W2067492711A5030451301 @default.
- W2067492711 hasAuthorship W2067492711A5041069711 @default.
- W2067492711 hasAuthorship W2067492711A5044791422 @default.
- W2067492711 hasAuthorship W2067492711A5063917475 @default.
- W2067492711 hasConcept C116073593 @default.
- W2067492711 hasConcept C134018914 @default.
- W2067492711 hasConcept C147483822 @default.
- W2067492711 hasConcept C150903083 @default.
- W2067492711 hasConcept C153911025 @default.
- W2067492711 hasConcept C163994747 @default.
- W2067492711 hasConcept C170493617 @default.
- W2067492711 hasConcept C181199279 @default.
- W2067492711 hasConcept C202751555 @default.
- W2067492711 hasConcept C203014093 @default.
- W2067492711 hasConcept C207001950 @default.
- W2067492711 hasConcept C24998067 @default.
- W2067492711 hasConcept C2779026604 @default.
- W2067492711 hasConcept C2779244956 @default.
- W2067492711 hasConcept C49382859 @default.
- W2067492711 hasConcept C54166955 @default.
- W2067492711 hasConcept C55493867 @default.
- W2067492711 hasConcept C7244527 @default.
- W2067492711 hasConcept C86803240 @default.
- W2067492711 hasConceptScore W2067492711C116073593 @default.
- W2067492711 hasConceptScore W2067492711C134018914 @default.
- W2067492711 hasConceptScore W2067492711C147483822 @default.
- W2067492711 hasConceptScore W2067492711C150903083 @default.
- W2067492711 hasConceptScore W2067492711C153911025 @default.
- W2067492711 hasConceptScore W2067492711C163994747 @default.
- W2067492711 hasConceptScore W2067492711C170493617 @default.
- W2067492711 hasConceptScore W2067492711C181199279 @default.
- W2067492711 hasConceptScore W2067492711C202751555 @default.
- W2067492711 hasConceptScore W2067492711C203014093 @default.
- W2067492711 hasConceptScore W2067492711C207001950 @default.
- W2067492711 hasConceptScore W2067492711C24998067 @default.
- W2067492711 hasConceptScore W2067492711C2779026604 @default.
- W2067492711 hasConceptScore W2067492711C2779244956 @default.
- W2067492711 hasConceptScore W2067492711C49382859 @default.
- W2067492711 hasConceptScore W2067492711C54166955 @default.
- W2067492711 hasConceptScore W2067492711C55493867 @default.
- W2067492711 hasConceptScore W2067492711C7244527 @default.
- W2067492711 hasConceptScore W2067492711C86803240 @default.
- W2067492711 hasIssue "2" @default.
- W2067492711 hasLocation W20674927111 @default.
- W2067492711 hasLocation W20674927112 @default.
- W2067492711 hasOpenAccess W2067492711 @default.
- W2067492711 hasPrimaryLocation W20674927111 @default.
- W2067492711 hasRelatedWork W162395500 @default.
- W2067492711 hasRelatedWork W1926631416 @default.
- W2067492711 hasRelatedWork W1972022723 @default.
- W2067492711 hasRelatedWork W2006122110 @default.