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- W2067493280 abstract "A new continuous cell line derived from an untreated human retinoblastoma has been established. This cell line, FMC-RB1 is strongly positive for common acute lymphoblastic leukemia antigen and shows a number of ring chromosomes and two marker chromosomes considered to be derivations of chromosome #17; the nonrandom chromosomal changes associated with retinoblastoma, particularly the loss of a chromosome #13 or the deletion of 13q14 was not observed. The establishment of the cell line initially required the presence of bone marrow stromal cells. Morphologically, this cell line grew as a suspension of small round cells in grape-like clusters with periodic “shedding” of single cells. FMC-RB1 could be cloned in soft agar, even in the absence of bone marrow stromal cells as “feeders,” making it suitable for a variety of biological studies." @default.
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- W2067493280 date "1986-02-01" @default.
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- W2067493280 title "A human retinoblastoma cell line expressing the common acute lymphoblastic leukemia antigen and displaying an unusual chromosome abnormality" @default.
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- W2067493280 doi "https://doi.org/10.1016/0165-4608(86)90094-4" @default.
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