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• W2067504499 abstract "Ethylene glycol (EG) can be found in many agents, such as antifreeze. Ingestion of EG may cause serious poisoning. Adults are typically exposed when EG is ingested as a cheap substitute for ethanol or in suicide-attempts. Children may be exposed by accidental ingestion caused by decantation of EG to unlabeled bottles. EG has in itself a low toxicity, but is in vivo broken down to four organic acids: glycoaldehyde, glycolic acid, glyoxylic acid and oxalic acid. The metabolites are cell toxins that cause central nervous system depression, and cardio-pulmonary and renal failure. Glycolic acid causes severe acidosis, and oxalate is precipitated as calcium oxalate in the kidneys and other tissues. We present five case reports of fatal EG-poisoning, and review the literature concerning clinical presentation and diagnosis, pathological findings, treatment and prevention." @default.
• W2067504499 created "2016-06-24" @default.
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• W2067504499 date "2005-12-01" @default.
• W2067504499 modified "2023-10-15" @default.
• W2067504499 title "Ethylene glycol poisoning" @default.
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• W2067504499 doi "https://doi.org/10.1016/j.forsciint.2004.11.012" @default.
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