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- W2067508178 abstract "This review summarizes the existing literature on sex differences in the effects of cannabinoid drugs on behavior, primarily in the adult rodent. These preclinical studies, taken together with preliminary reports of sex differences in cannabinoid effects in humans, suggest that sex of subject may be an important modulating factor in a variety of cannabinoid effects. When sex differences are found, females are usually more sensitive than males to cannabinoids. Both pharmacokinetic and pharmacodynamic variables may contribute to sex differences in behavioral effects of cannabinoids. Given the significant therapeutic potential of cannabinoid agonists and antagonists — as well as their widespread recreational use — it will be important to determine the reliability and functional significance of, as well as mechanisms underlying sex differences in cannabinoid effects." @default.
- W2067508178 created "2016-06-24" @default.
- W2067508178 creator A5041895158 @default.
- W2067508178 date "2005-09-01" @default.
- W2067508178 modified "2023-09-26" @default.
- W2067508178 title "Sex differences in behavioral effects of cannabinoids" @default.
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- W2067508178 doi "https://doi.org/10.1016/j.lfs.2005.04.019" @default.
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