Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067510631> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2067510631 endingPage "1070" @default.
- W2067510631 startingPage "1065" @default.
- W2067510631 abstract "Abstract Objective —To evaluate the safety and efficacy of an experimental adjuvanted DNA-plasmid vaccine against West Nile virus (WNV) in red-tailed hawks ( Buteo jamaicensis ). Animals —19 permanently disabled but otherwise healthy red-tailed hawks of mixed ages and both sexes without detectable serum antibodies against WNV. Procedures —Hawks were injected IM with an experimental WNV DNA-plasmid vaccine in an aluminum-phosphate adjuvant (n = 14) or with the adjuvant only (control group; 5). All birds received 2 injections at a 3-week interval. Blood samples for serologic evaluation were collected before the first injection and 4 weeks after the second injection (day 0). At day 0, hawks were injected SC with live WNV. Pre- and postchallenge blood samples were collected at intervals for 14 days for assessment of viremia and antibody determination; oropharyngeal and cloacal swabs were collected for assessment of viral shedding. Results —Vaccination was not associated with morbidity or deaths. Three of the vaccinated birds seroconverted after the second vaccine injection; all other birds seroconverted following the live virus injection. Vaccinated birds had significantly less severe viremia and shorter and less-intense shedding periods, compared with the control birds. Conclusions and Clinical Relevance —Use of the WNV DNA-plasmid vaccine in red-tailed hawks was safe, and vaccination attenuated but did not eliminate both the viremia and the intensity of postchallenge shedding following live virus exposure. Further research is warranted to conclusively determine the efficacy of this vaccine preparation for protection of red-tailed hawks and other avian species against WNV-induced disease." @default.
- W2067510631 created "2016-06-24" @default.
- W2067510631 creator A5004690409 @default.
- W2067510631 creator A5013078751 @default.
- W2067510631 creator A5034917151 @default.
- W2067510631 creator A5053147162 @default.
- W2067510631 creator A5062699143 @default.
- W2067510631 creator A5072938842 @default.
- W2067510631 date "2011-08-01" @default.
- W2067510631 modified "2023-09-26" @default.
- W2067510631 title "Effect of West Nile virus DNA-plasmid vaccination on response to live virus challenge in red-tailed hawks (Buteo jamaicensis)" @default.
- W2067510631 cites W1975639180 @default.
- W2067510631 cites W1994841440 @default.
- W2067510631 cites W2021385074 @default.
- W2067510631 cites W2021410341 @default.
- W2067510631 cites W2022942428 @default.
- W2067510631 cites W2033094913 @default.
- W2067510631 cites W2036782847 @default.
- W2067510631 cites W2065310153 @default.
- W2067510631 cites W2078198441 @default.
- W2067510631 cites W2086724355 @default.
- W2067510631 cites W2087544926 @default.
- W2067510631 cites W2097250203 @default.
- W2067510631 cites W2108336788 @default.
- W2067510631 cites W2123228311 @default.
- W2067510631 cites W2125147092 @default.
- W2067510631 cites W2153464338 @default.
- W2067510631 cites W2154674078 @default.
- W2067510631 cites W2154932162 @default.
- W2067510631 cites W2156421396 @default.
- W2067510631 cites W2163399038 @default.
- W2067510631 cites W2178836796 @default.
- W2067510631 doi "https://doi.org/10.2460/ajvr.72.8.1065" @default.
- W2067510631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21801064" @default.
- W2067510631 hasPublicationYear "2011" @default.
- W2067510631 type Work @default.
- W2067510631 sameAs 2067510631 @default.
- W2067510631 citedByCount "19" @default.
- W2067510631 countsByYear W20675106312013 @default.
- W2067510631 countsByYear W20675106312014 @default.
- W2067510631 countsByYear W20675106312015 @default.
- W2067510631 countsByYear W20675106312016 @default.
- W2067510631 countsByYear W20675106312017 @default.
- W2067510631 countsByYear W20675106312018 @default.
- W2067510631 countsByYear W20675106312019 @default.
- W2067510631 countsByYear W20675106312022 @default.
- W2067510631 countsByYear W20675106312023 @default.
- W2067510631 crossrefType "journal-article" @default.
- W2067510631 hasAuthorship W2067510631A5004690409 @default.
- W2067510631 hasAuthorship W2067510631A5013078751 @default.
- W2067510631 hasAuthorship W2067510631A5034917151 @default.
- W2067510631 hasAuthorship W2067510631A5053147162 @default.
- W2067510631 hasAuthorship W2067510631A5062699143 @default.
- W2067510631 hasAuthorship W2067510631A5072938842 @default.
- W2067510631 hasConcept C12914427 @default.
- W2067510631 hasConcept C134215735 @default.
- W2067510631 hasConcept C159047783 @default.
- W2067510631 hasConcept C188382862 @default.
- W2067510631 hasConcept C18903297 @default.
- W2067510631 hasConcept C22070199 @default.
- W2067510631 hasConcept C2522874641 @default.
- W2067510631 hasConcept C2776185481 @default.
- W2067510631 hasConcept C2778261623 @default.
- W2067510631 hasConcept C42972112 @default.
- W2067510631 hasConcept C71924100 @default.
- W2067510631 hasConcept C86803240 @default.
- W2067510631 hasConceptScore W2067510631C12914427 @default.
- W2067510631 hasConceptScore W2067510631C134215735 @default.
- W2067510631 hasConceptScore W2067510631C159047783 @default.
- W2067510631 hasConceptScore W2067510631C188382862 @default.
- W2067510631 hasConceptScore W2067510631C18903297 @default.
- W2067510631 hasConceptScore W2067510631C22070199 @default.
- W2067510631 hasConceptScore W2067510631C2522874641 @default.
- W2067510631 hasConceptScore W2067510631C2776185481 @default.
- W2067510631 hasConceptScore W2067510631C2778261623 @default.
- W2067510631 hasConceptScore W2067510631C42972112 @default.
- W2067510631 hasConceptScore W2067510631C71924100 @default.
- W2067510631 hasConceptScore W2067510631C86803240 @default.
- W2067510631 hasIssue "8" @default.
- W2067510631 hasLocation W20675106311 @default.
- W2067510631 hasLocation W20675106312 @default.
- W2067510631 hasOpenAccess W2067510631 @default.
- W2067510631 hasPrimaryLocation W20675106311 @default.
- W2067510631 hasRelatedWork W1933588764 @default.
- W2067510631 hasRelatedWork W1987592857 @default.
- W2067510631 hasRelatedWork W2036754569 @default.
- W2067510631 hasRelatedWork W2057745002 @default.
- W2067510631 hasRelatedWork W2082080978 @default.
- W2067510631 hasRelatedWork W2094603343 @default.
- W2067510631 hasRelatedWork W2127817946 @default.
- W2067510631 hasRelatedWork W2150845218 @default.
- W2067510631 hasRelatedWork W2166925281 @default.
- W2067510631 hasRelatedWork W2901087267 @default.
- W2067510631 hasVolume "72" @default.
- W2067510631 isParatext "false" @default.
- W2067510631 isRetracted "false" @default.
- W2067510631 magId "2067510631" @default.
- W2067510631 workType "article" @default.