FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067535355> ?p ?o ?g. }

• W2067535355 abstract "Alterations in glutamate transporter expression are closely related to opiate addition behavior, but the role of opioid receptors is unclear. In this study, we used primary cultures of hippocampal neurons from neonatal rats to study the effects of chronic exposure to morphine on excitatory amino acid transporter 3 (EAAT3) expression and the roles of µ opioid receptor (MOR), δ opioid receptor (DOR), and κ opioid receptor (KOR) in the morphine-dependent alterations in EAAT3 expression. The results showed that the EAAT3 protein and mRNA expression levels decreased significantly after chronic exposure to morphine (10μmol/L) for 48h, whereas the concentration of extracellular glutamate increased. In addition, we found that both the MOR inhibitor CTOP and the DOR inhibitor naltrindole could reverse the decreased expression of EAAT3 after exposure to morphine, whereas the MOR activator DAMGO and the DOR activator DPDPE significantly decreased EAAT3 expression. The KOR inhibitor had no effect on the expression of EAAT3, whereas its activator increased EAAT3 expression. These results suggest that the down-regulation of morphine-dependent EAAT3 expression in primary rat hippocampal cultures may be mediated by MOR and DOR and that KOR may not contribute significantly to this effect." @default.
• W2067535355 created "2016-06-24" @default.
• W2067535355 creator A5003125273 @default.
• W2067535355 creator A5003525882 @default.
• W2067535355 creator A5015736153 @default.
• W2067535355 creator A5017292840 @default.
• W2067535355 creator A5022825744 @default.
• W2067535355 creator A5052679781 @default.
• W2067535355 creator A5071474999 @default.
• W2067535355 date "2015-12-01" @default.
• W2067535355 modified "2023-09-26" @default.
• W2067535355 title "Chronic exposure to morphine decreases the expression of EAAT3 via opioid receptors in hippocampal neurons" @default.
• W2067535355 cites W1540277158 @default.
• W2067535355 cites W1967262742 @default.
• W2067535355 cites W1978972745 @default.
• W2067535355 cites W1979566078 @default.
• W2067535355 cites W1988489044 @default.
• W2067535355 cites W2000204883 @default.
• W2067535355 cites W2000607451 @default.
• W2067535355 cites W2002366377 @default.
• W2067535355 cites W2007745798 @default.
• W2067535355 cites W2024031866 @default.
• W2067535355 cites W2026262374 @default.
• W2067535355 cites W2061588957 @default.
• W2067535355 cites W2067147530 @default.
• W2067535355 cites W2079322667 @default.
• W2067535355 cites W2087221285 @default.
• W2067535355 cites W2090913637 @default.
• W2067535355 cites W2091395194 @default.
• W2067535355 cites W2098885564 @default.
• W2067535355 cites W2111806354 @default.
• W2067535355 cites W2116447221 @default.
• W2067535355 cites W2117310045 @default.
• W2067535355 cites W2130791243 @default.
• W2067535355 cites W2143046795 @default.
• W2067535355 cites W2774194419 @default.
• W2067535355 cites W775019103 @default.
• W2067535355 doi "https://doi.org/10.1016/j.brainres.2015.03.037" @default.
• W2067535355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25839761" @default.
• W2067535355 hasPublicationYear "2015" @default.
• W2067535355 type Work @default.
• W2067535355 sameAs 2067535355 @default.
• W2067535355 citedByCount "12" @default.
• W2067535355 countsByYear W20675353552016 @default.
• W2067535355 countsByYear W20675353552017 @default.
• W2067535355 countsByYear W20675353552018 @default.
• W2067535355 countsByYear W20675353552019 @default.
• W2067535355 countsByYear W20675353552021 @default.
• W2067535355 countsByYear W20675353552023 @default.
• W2067535355 crossrefType "journal-article" @default.
• W2067535355 hasAuthorship W2067535355A5003125273 @default.
• W2067535355 hasAuthorship W2067535355A5003525882 @default.
• W2067535355 hasAuthorship W2067535355A5015736153 @default.
• W2067535355 hasAuthorship W2067535355A5017292840 @default.
• W2067535355 hasAuthorship W2067535355A5022825744 @default.
• W2067535355 hasAuthorship W2067535355A5052679781 @default.
• W2067535355 hasAuthorship W2067535355A5071474999 @default.
• W2067535355 hasConcept C126322002 @default.
• W2067535355 hasConcept C134018914 @default.
• W2067535355 hasConcept C14397066 @default.
• W2067535355 hasConcept C148762608 @default.
• W2067535355 hasConcept C170493617 @default.
• W2067535355 hasConcept C185592680 @default.
• W2067535355 hasConcept C2776401185 @default.
• W2067535355 hasConcept C2777389121 @default.
• W2067535355 hasConcept C2777953665 @default.
• W2067535355 hasConcept C2779886867 @default.
• W2067535355 hasConcept C2781063702 @default.
• W2067535355 hasConcept C2993002077 @default.
• W2067535355 hasConcept C61174792 @default.
• W2067535355 hasConcept C71924100 @default.
• W2067535355 hasConcept C88045685 @default.
• W2067535355 hasConcept C98274493 @default.
• W2067535355 hasConceptScore W2067535355C126322002 @default.
• W2067535355 hasConceptScore W2067535355C134018914 @default.
• W2067535355 hasConceptScore W2067535355C14397066 @default.
• W2067535355 hasConceptScore W2067535355C148762608 @default.
• W2067535355 hasConceptScore W2067535355C170493617 @default.
• W2067535355 hasConceptScore W2067535355C185592680 @default.
• W2067535355 hasConceptScore W2067535355C2776401185 @default.
• W2067535355 hasConceptScore W2067535355C2777389121 @default.
• W2067535355 hasConceptScore W2067535355C2777953665 @default.
• W2067535355 hasConceptScore W2067535355C2779886867 @default.
• W2067535355 hasConceptScore W2067535355C2781063702 @default.
• W2067535355 hasConceptScore W2067535355C2993002077 @default.
• W2067535355 hasConceptScore W2067535355C61174792 @default.
• W2067535355 hasConceptScore W2067535355C71924100 @default.
• W2067535355 hasConceptScore W2067535355C88045685 @default.
• W2067535355 hasConceptScore W2067535355C98274493 @default.
• W2067535355 hasFunder F4320321001 @default.
• W2067535355 hasLocation W20675353551 @default.
• W2067535355 hasLocation W20675353552 @default.
• W2067535355 hasOpenAccess W2067535355 @default.
• W2067535355 hasPrimaryLocation W20675353551 @default.
• W2067535355 hasRelatedWork W1968272849 @default.
• W2067535355 hasRelatedWork W1975659701 @default.
• W2067535355 hasRelatedWork W1986886837 @default.
• W2067535355 hasRelatedWork W2011560496 @default.
• W2067535355 hasRelatedWork W2045120136 @default.
• W2067535355 hasRelatedWork W2067535355 @default.

• next