FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067652095> ?p ?o ?g. }

• W2067652095 endingPage "556" @default.
• W2067652095 startingPage "552" @default.
• W2067652095 abstract "<h3>Background:</h3> Neuronal abnormalities are associated with the pathogenesis of diabetic retinopathy. However, the mechanisms for neuronal cell death in diabetic retinopathy remain unclear. <h3>Aim:</h3> To determine whether altered expression of Bax, caspase-9 and -3 is associated with degenerative neurons in diabetic retinopathy. <h3>Methods:</h3> Immunohistochemistry was performed on cryosections obtained from five pairs of normal and five pairs of age-matched diabetic human retinas. Diabetic eyes had no proliferative diabetic retinopathy and no histories of photocoagulation or ocular surgery. In this study, Fluoro-Jade B (FJB) was used as a marker for identification of degenerative neurons. <h3>Results:</h3> In diabetic retinas, Bax overexpression coexisted with FJB positive signals in the ganglion cell layer (GCL) compared with very low FJB levels in the normal retina. Increased level of the active forms of caspase-9 and -3 expressions coexisted with FJB positive cells in the GCL of diabetic retinas compared with those in normal retinas. <h3>Conclusions:</h3> Upregulation of Bax, caspase-9 and -3 expression was associated with neuronal degeneration in diabetic retinopathy. The mitochondria- and caspase-dependent cell-death pathway may be, in part, associated with neuronal degeneration in diabetic retinas." @default.
• W2067652095 created "2016-06-24" @default.
• W2067652095 creator A5010652719 @default.
• W2067652095 creator A5027211308 @default.
• W2067652095 creator A5032451456 @default.
• W2067652095 creator A5085497567 @default.
• W2067652095 date "2008-03-27" @default.
• W2067652095 modified "2023-10-15" @default.
• W2067652095 title "Mitochondria- and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy" @default.
• W2067652095 cites W1487972772 @default.
• W2067652095 cites W1577083025 @default.
• W2067652095 cites W1644794975 @default.
• W2067652095 cites W1973953770 @default.
• W2067652095 cites W1982523473 @default.
• W2067652095 cites W1985052245 @default.
• W2067652095 cites W1987581956 @default.
• W2067652095 cites W1993968665 @default.
• W2067652095 cites W2004709704 @default.
• W2067652095 cites W2026761074 @default.
• W2067652095 cites W2030321966 @default.
• W2067652095 cites W2036289958 @default.
• W2067652095 cites W2045753004 @default.
• W2067652095 cites W2049838321 @default.
• W2067652095 cites W2075255898 @default.
• W2067652095 cites W2077726387 @default.
• W2067652095 cites W2081319561 @default.
• W2067652095 cites W2126327941 @default.
• W2067652095 cites W2130816682 @default.
• W2067652095 cites W2138549894 @default.
• W2067652095 doi "https://doi.org/10.1136/bjo.2007.132308" @default.
• W2067652095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18369072" @default.
• W2067652095 hasPublicationYear "2008" @default.
• W2067652095 type Work @default.
• W2067652095 sameAs 2067652095 @default.
• W2067652095 citedByCount "89" @default.
• W2067652095 countsByYear W20676520952012 @default.
• W2067652095 countsByYear W20676520952013 @default.
• W2067652095 countsByYear W20676520952014 @default.
• W2067652095 countsByYear W20676520952015 @default.
• W2067652095 countsByYear W20676520952016 @default.
• W2067652095 countsByYear W20676520952017 @default.
• W2067652095 countsByYear W20676520952019 @default.
• W2067652095 countsByYear W20676520952020 @default.
• W2067652095 countsByYear W20676520952021 @default.
• W2067652095 countsByYear W20676520952022 @default.
• W2067652095 countsByYear W20676520952023 @default.
• W2067652095 crossrefType "journal-article" @default.
• W2067652095 hasAuthorship W2067652095A5010652719 @default.
• W2067652095 hasAuthorship W2067652095A5027211308 @default.
• W2067652095 hasAuthorship W2067652095A5032451456 @default.
• W2067652095 hasAuthorship W2067652095A5085497567 @default.
• W2067652095 hasConcept C104317684 @default.
• W2067652095 hasConcept C118487528 @default.
• W2067652095 hasConcept C127561419 @default.
• W2067652095 hasConcept C134018914 @default.
• W2067652095 hasConcept C142724271 @default.
• W2067652095 hasConcept C169760540 @default.
• W2067652095 hasConcept C190283241 @default.
• W2067652095 hasConcept C204232928 @default.
• W2067652095 hasConcept C2777093970 @default.
• W2067652095 hasConcept C2778313320 @default.
• W2067652095 hasConcept C2779829184 @default.
• W2067652095 hasConcept C2780942790 @default.
• W2067652095 hasConcept C28859421 @default.
• W2067652095 hasConcept C31573885 @default.
• W2067652095 hasConcept C55493867 @default.
• W2067652095 hasConcept C555293320 @default.
• W2067652095 hasConcept C71924100 @default.
• W2067652095 hasConcept C86803240 @default.
• W2067652095 hasConcept C95444343 @default.
• W2067652095 hasConcept C98424977 @default.
• W2067652095 hasConceptScore W2067652095C104317684 @default.
• W2067652095 hasConceptScore W2067652095C118487528 @default.
• W2067652095 hasConceptScore W2067652095C127561419 @default.
• W2067652095 hasConceptScore W2067652095C134018914 @default.
• W2067652095 hasConceptScore W2067652095C142724271 @default.
• W2067652095 hasConceptScore W2067652095C169760540 @default.
• W2067652095 hasConceptScore W2067652095C190283241 @default.
• W2067652095 hasConceptScore W2067652095C204232928 @default.
• W2067652095 hasConceptScore W2067652095C2777093970 @default.
• W2067652095 hasConceptScore W2067652095C2778313320 @default.
• W2067652095 hasConceptScore W2067652095C2779829184 @default.
• W2067652095 hasConceptScore W2067652095C2780942790 @default.
• W2067652095 hasConceptScore W2067652095C28859421 @default.
• W2067652095 hasConceptScore W2067652095C31573885 @default.
• W2067652095 hasConceptScore W2067652095C55493867 @default.
• W2067652095 hasConceptScore W2067652095C555293320 @default.
• W2067652095 hasConceptScore W2067652095C71924100 @default.
• W2067652095 hasConceptScore W2067652095C86803240 @default.
• W2067652095 hasConceptScore W2067652095C95444343 @default.
• W2067652095 hasConceptScore W2067652095C98424977 @default.
• W2067652095 hasIssue "4" @default.
• W2067652095 hasLocation W20676520951 @default.
• W2067652095 hasLocation W20676520952 @default.
• W2067652095 hasOpenAccess W2067652095 @default.
• W2067652095 hasPrimaryLocation W20676520951 @default.
• W2067652095 hasRelatedWork W1670069535 @default.
• W2067652095 hasRelatedWork W1996479442 @default.

• next