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- W2067659097 abstract "The utilization rates of D-[15N] valine, D-[15N] leucine, D-[15N] phenylalanine and D-[15N] alanine were investigated in seven infants being fed parenterally. Retention of the (15)N in the protein pool varied from one amino acid to another and ranged from 23.2% for D-[15N] valine to 48.6% for D-[15N] alanine. In the case of valine it was shown that cumulative renal excretion amounted to 70% of the applied (15)N-dose, 44% being overflow of unchanged D-[15N] valine, 16.6% appearing as [15N] urea and 1.2% as [15N] ammonium. This indicates that doubling the concentrations of D-amino acid racemates compared with their L-isomer counterparts in parenteral feeding solutions must inevitably lead to imbalances. The use of D-amino acids for the purposes of parenteral nutrition remains however ineffective due to their poor and variable utilization compared to L-amino acids." @default.
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- W2067659097 date "1983-04-01" @default.
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- W2067659097 title "D-amino acid utilization in infants measured with the 15N-tracer technique" @default.
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- W2067659097 doi "https://doi.org/10.1016/0261-5614(83)90027-4" @default.
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