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- W2067681194 abstract "Des définitions internationalement reconnues des syndromes septiques sont disponibles, permettant d’homogénéiser les essais cliniques. Près de 15 % des malades hospitalisés en réanimation ont un syndrome septique grave, dont les 2/3 ont un choc septique. On estime qu’en France, environ 75 000 syndromes septiques graves sont hospitalisés en réanimation, et la fréquence de ces syndromes s’accroît. La mortalité hospitalière est de 20 % en cas de sepsis simple de 40 % et au-delà en cas de syndrome septique grave ou de choc; elle tend cependant à s’améliorer depuis une dizaine d’années. Le pronostic est fonction de la gravité des dysfonctions d’organe, en particulier de la défaillance cardiovasculaire. Une identification précoce des syndromes septiques et des malades à risque d’évolution vers un choc septique, associée à une intervention rapide visant en particulier à corriger les troubles hémodynamiques, sont susceptibles d’améliorer le pronostic. Internationally recognized definitions of septic syndromes are available and make it possible to conduct more homogenous clinical trials. Nearly 15% of patients in intensive care have severe sepsis and two thirds of them septic shock. In France, it is estimated that approximately 75 000 patients with severe sepsis are admitted to intensive care units, and the frequency of sepsis is increasing. Hospital mortality is 20% for simple sepsis and 40% and higher for cases of severe sepsis or septic shock; it has nonetheless been improving over the past decade. Prognosis depends on the severity of organ dysfunctions in particular, of cardiovascular failure. Early identification of sepsis and of patients at risk of developing septic shock, together with rapid intervention aiming especially to correct hemodynamic disorders, is likely to improve prognosis." @default.
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- W2067681194 date "2006-03-01" @default.
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- W2067681194 title "Épidémiologie des états septiques graves" @default.
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- W2067681194 doi "https://doi.org/10.1016/s0755-4982(06)74627-9" @default.
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