Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067681667> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2067681667 endingPage "272" @default.
- W2067681667 startingPage "265" @default.
- W2067681667 abstract "The displacement of [3H]flunitrazepam by unlabelled flunitrazepam or zolpidem was used to assess the affinity and density of sub-types of GABA(A) receptors in the superior frontal and primary motor cortices of ten alcoholic, seven alcoholic-cirrhotic and ten matched control cases. The binding was best fitted by a model with a single site for flunitrazepam, but two sites for zolpidem. Neither the patients' age nor the post-mortem interval were significantly correlated with the affinity or density of any of the binding sites. The affinity of all ligands did not differ either between cortical regions or across case groups. Hence, the density of each binding site was analyzed at constant affinity. The densities of flunitrazepam and high-affinity zolpidem binding sites were invariant across cortical regions and case groups. Low-affinity zolpidem binding sites were significantly more dense in the frontal than in the motor cortex of alcoholic cases irrespective of cirrhosis, whereas this regional difference was not significant in control cases." @default.
- W2067681667 created "2016-06-24" @default.
- W2067681667 creator A5030356025 @default.
- W2067681667 creator A5059609950 @default.
- W2067681667 creator A5061212086 @default.
- W2067681667 date "1997-05-01" @default.
- W2067681667 modified "2023-10-06" @default.
- W2067681667 title "Zolpidem binding sites on the GABAA receptor in brain from human cirrhotic and non-cirrhotic alcoholics" @default.
- W2067681667 cites W145363236 @default.
- W2067681667 cites W1557959115 @default.
- W2067681667 cites W1775749144 @default.
- W2067681667 cites W1987753347 @default.
- W2067681667 cites W1996039145 @default.
- W2067681667 cites W1998184150 @default.
- W2067681667 cites W1998971005 @default.
- W2067681667 cites W1999287710 @default.
- W2067681667 cites W2014836652 @default.
- W2067681667 cites W2023468172 @default.
- W2067681667 cites W2027908241 @default.
- W2067681667 cites W2030929795 @default.
- W2067681667 cites W2043813981 @default.
- W2067681667 cites W2054272209 @default.
- W2067681667 cites W2059864318 @default.
- W2067681667 cites W2072497313 @default.
- W2067681667 cites W2072498668 @default.
- W2067681667 cites W2076501023 @default.
- W2067681667 cites W2083852352 @default.
- W2067681667 cites W2084287988 @default.
- W2067681667 cites W2086968601 @default.
- W2067681667 cites W2094838820 @default.
- W2067681667 cites W2095684169 @default.
- W2067681667 cites W2128692167 @default.
- W2067681667 cites W2158624080 @default.
- W2067681667 doi "https://doi.org/10.1016/s0014-2999(97)85422-2" @default.
- W2067681667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9196280" @default.
- W2067681667 hasPublicationYear "1997" @default.
- W2067681667 type Work @default.
- W2067681667 sameAs 2067681667 @default.
- W2067681667 citedByCount "22" @default.
- W2067681667 countsByYear W20676816672012 @default.
- W2067681667 countsByYear W20676816672013 @default.
- W2067681667 countsByYear W20676816672016 @default.
- W2067681667 crossrefType "journal-article" @default.
- W2067681667 hasAuthorship W2067681667A5030356025 @default.
- W2067681667 hasAuthorship W2067681667A5059609950 @default.
- W2067681667 hasAuthorship W2067681667A5061212086 @default.
- W2067681667 hasConcept C107824862 @default.
- W2067681667 hasConcept C126322002 @default.
- W2067681667 hasConcept C134018914 @default.
- W2067681667 hasConcept C168258287 @default.
- W2067681667 hasConcept C170493617 @default.
- W2067681667 hasConcept C185592680 @default.
- W2067681667 hasConcept C2777123777 @default.
- W2067681667 hasConcept C2781041448 @default.
- W2067681667 hasConcept C2781210498 @default.
- W2067681667 hasConcept C2781442855 @default.
- W2067681667 hasConcept C55493867 @default.
- W2067681667 hasConcept C71924100 @default.
- W2067681667 hasConcept C98274493 @default.
- W2067681667 hasConceptScore W2067681667C107824862 @default.
- W2067681667 hasConceptScore W2067681667C126322002 @default.
- W2067681667 hasConceptScore W2067681667C134018914 @default.
- W2067681667 hasConceptScore W2067681667C168258287 @default.
- W2067681667 hasConceptScore W2067681667C170493617 @default.
- W2067681667 hasConceptScore W2067681667C185592680 @default.
- W2067681667 hasConceptScore W2067681667C2777123777 @default.
- W2067681667 hasConceptScore W2067681667C2781041448 @default.
- W2067681667 hasConceptScore W2067681667C2781210498 @default.
- W2067681667 hasConceptScore W2067681667C2781442855 @default.
- W2067681667 hasConceptScore W2067681667C55493867 @default.
- W2067681667 hasConceptScore W2067681667C71924100 @default.
- W2067681667 hasConceptScore W2067681667C98274493 @default.
- W2067681667 hasIssue "2-3" @default.
- W2067681667 hasLocation W20676816671 @default.
- W2067681667 hasLocation W20676816672 @default.
- W2067681667 hasOpenAccess W2067681667 @default.
- W2067681667 hasPrimaryLocation W20676816671 @default.
- W2067681667 hasRelatedWork W1190248987 @default.
- W2067681667 hasRelatedWork W1965818198 @default.
- W2067681667 hasRelatedWork W2024017841 @default.
- W2067681667 hasRelatedWork W2041077726 @default.
- W2067681667 hasRelatedWork W2053774301 @default.
- W2067681667 hasRelatedWork W2058737540 @default.
- W2067681667 hasRelatedWork W2137738732 @default.
- W2067681667 hasRelatedWork W2162515150 @default.
- W2067681667 hasRelatedWork W2810500669 @default.
- W2067681667 hasRelatedWork W4234065699 @default.
- W2067681667 hasVolume "326" @default.
- W2067681667 isParatext "false" @default.
- W2067681667 isRetracted "false" @default.
- W2067681667 magId "2067681667" @default.
- W2067681667 workType "article" @default.