FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2067681732> ?p ?o ?g. }

• W2067681732 abstract "Dendritic cell (DC)-based tumor immunotherapy is widely known to elicit protective anti-tumor immune responses, although the safety and effectiveness have yet to be thoroughly explored. We reported that a disruption in the stratum corneum barrier resulted in enhanced permeability and alterations in the skin immune system in such a way that epidermal Langerhans cells (LCs) functioned as vigorous antigen presenters for T helper (Th) cells and cytotoxic T lymphocytes (CTLs). In both human and murine models, topical application of melanoma-associated antigen peptides onto stratum corneum barrier-disrupted skin, specifically induced tumoricidal immune responses in vivo and in vitro accompanying an increased expression of MHC and co-stimulatory molecules on LCs. In addition, for reasons of simplicity, safety and effectiveness, percutaneous peptide application has demonstrated a certain degree of feasibility in clinical approach in patients with melanoma. In the future, resolution of some of the outstanding issues concerning the selection of the most effective adjuvants in combination with barrier disruption and depletion of regulatory T (Treg) cell-mediated immune suppression would appear as essential to improve percutaneous melanoma immunotherapy." @default.
• W2067681732 created "2016-06-24" @default.
• W2067681732 creator A5015963255 @default.
• W2067681732 creator A5064148704 @default.
• W2067681732 date "2007-11-01" @default.
• W2067681732 modified "2023-09-25" @default.
• W2067681732 title "The current status and future direction of percutaneous peptide immunization against melanoma" @default.
• W2067681732 cites W1538092336 @default.
• W2067681732 cites W1549346812 @default.
• W2067681732 cites W1814576137 @default.
• W2067681732 cites W1929074972 @default.
• W2067681732 cites W1969013826 @default.
• W2067681732 cites W1970511901 @default.
• W2067681732 cites W1974692569 @default.
• W2067681732 cites W1985336603 @default.
• W2067681732 cites W1986199198 @default.
• W2067681732 cites W1995871097 @default.
• W2067681732 cites W2006327502 @default.
• W2067681732 cites W2013058375 @default.
• W2067681732 cites W2015780294 @default.
• W2067681732 cites W2028159810 @default.
• W2067681732 cites W2028593992 @default.
• W2067681732 cites W2031542083 @default.
• W2067681732 cites W2043352390 @default.
• W2067681732 cites W2048106461 @default.
• W2067681732 cites W2059762191 @default.
• W2067681732 cites W2064846310 @default.
• W2067681732 cites W2068364493 @default.
• W2067681732 cites W2070794029 @default.
• W2067681732 cites W2071157382 @default.
• W2067681732 cites W2076819781 @default.
• W2067681732 cites W2081767375 @default.
• W2067681732 cites W2083932142 @default.
• W2067681732 cites W2086133317 @default.
• W2067681732 cites W2088742697 @default.
• W2067681732 cites W2090020002 @default.
• W2067681732 cites W2092282518 @default.
• W2067681732 cites W2098675808 @default.
• W2067681732 cites W2106081822 @default.
• W2067681732 cites W2107408397 @default.
• W2067681732 cites W2110404633 @default.
• W2067681732 cites W2126043466 @default.
• W2067681732 cites W2130311074 @default.
• W2067681732 cites W2134768631 @default.
• W2067681732 cites W2142501626 @default.
• W2067681732 cites W2151937278 @default.
• W2067681732 cites W2152627678 @default.
• W2067681732 cites W2270737010 @default.
• W2067681732 cites W2513724291 @default.
• W2067681732 cites W2582398023 @default.
• W2067681732 cites W3141900223 @default.
• W2067681732 doi "https://doi.org/10.1016/j.jdermsci.2007.05.004" @default.
• W2067681732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17719748" @default.
• W2067681732 hasPublicationYear "2007" @default.
• W2067681732 type Work @default.
• W2067681732 sameAs 2067681732 @default.
• W2067681732 citedByCount "6" @default.
• W2067681732 countsByYear W20676817322012 @default.
• W2067681732 countsByYear W20676817322014 @default.
• W2067681732 crossrefType "journal-article" @default.
• W2067681732 hasAuthorship W2067681732A5015963255 @default.
• W2067681732 hasAuthorship W2067681732A5064148704 @default.
• W2067681732 hasConcept C142724271 @default.
• W2067681732 hasConcept C147483822 @default.
• W2067681732 hasConcept C150903083 @default.
• W2067681732 hasConcept C154317977 @default.
• W2067681732 hasConcept C202751555 @default.
• W2067681732 hasConcept C203014093 @default.
• W2067681732 hasConcept C207001950 @default.
• W2067681732 hasConcept C2777658100 @default.
• W2067681732 hasConcept C2777701055 @default.
• W2067681732 hasConcept C2778370115 @default.
• W2067681732 hasConcept C502942594 @default.
• W2067681732 hasConcept C55493867 @default.
• W2067681732 hasConcept C71924100 @default.
• W2067681732 hasConcept C86803240 @default.
• W2067681732 hasConcept C8891405 @default.
• W2067681732 hasConceptScore W2067681732C142724271 @default.
• W2067681732 hasConceptScore W2067681732C147483822 @default.
• W2067681732 hasConceptScore W2067681732C150903083 @default.
• W2067681732 hasConceptScore W2067681732C154317977 @default.
• W2067681732 hasConceptScore W2067681732C202751555 @default.
• W2067681732 hasConceptScore W2067681732C203014093 @default.
• W2067681732 hasConceptScore W2067681732C207001950 @default.
• W2067681732 hasConceptScore W2067681732C2777658100 @default.
• W2067681732 hasConceptScore W2067681732C2777701055 @default.
• W2067681732 hasConceptScore W2067681732C2778370115 @default.
• W2067681732 hasConceptScore W2067681732C502942594 @default.
• W2067681732 hasConceptScore W2067681732C55493867 @default.
• W2067681732 hasConceptScore W2067681732C71924100 @default.
• W2067681732 hasConceptScore W2067681732C86803240 @default.
• W2067681732 hasConceptScore W2067681732C8891405 @default.
• W2067681732 hasLocation W20676817321 @default.
• W2067681732 hasLocation W20676817322 @default.
• W2067681732 hasOpenAccess W2067681732 @default.
• W2067681732 hasPrimaryLocation W20676817321 @default.
• W2067681732 hasRelatedWork W2001055320 @default.
• W2067681732 hasRelatedWork W2008949385 @default.
• W2067681732 hasRelatedWork W2054529397 @default.
• W2067681732 hasRelatedWork W2091514695 @default.

• next