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- W2067706965 endingPage "242" @default.
- W2067706965 startingPage "235" @default.
- W2067706965 abstract "Neurotrophic factors, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), are known to play a crucial role in growth, differentiation and function in a variety of brain neurons during development and in adult life. We have recently shown that environmental changes, aggressive behavior and anxiety-like responses alter both circulating and brain basal NGF levels. In the present review, we present data obtained using animal models which suggest that neurotrophic factors, particularly NGF and BDNF, might be implicated in mechanism(s) leading to a condition associated with schizophrenic-like behaviors. The hypothesis that neurotrophins of the NGF family can be implicated in some maldevelopmental aspects of schizophrenia is supported by findings indicating that the constitutive levels of NGF and BDNF are affected in schizophrenic patients." @default.
- W2067706965 created "2016-06-24" @default.
- W2067706965 creator A5018870384 @default.
- W2067706965 creator A5040486809 @default.
- W2067706965 creator A5050470684 @default.
- W2067706965 creator A5058211896 @default.
- W2067706965 creator A5064944598 @default.
- W2067706965 date "2000-06-01" @default.
- W2067706965 modified "2023-09-23" @default.
- W2067706965 title "Studies in animal models and humans suggesting a role of nerve growth factor in schizophrenia-like disorders" @default.
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